CyClus3D: a Cytoscape plugin for clustering network motifs in integrated networks
CyClus3D: a Cytoscape plugin for clustering network motifs in integrated networks
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DOI：
10.1093/bioinformatics/btr182
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发表时间：
2011-06-01
期刊：
影响因子：
5.8
通讯作者：
Michoel, Tom
中科院分区：
文献类型：
--
作者：
Audenaert, Pieter;Van Parys, Thomas;Michoel, Tom
集成分子网络中的网络基序代表不同数据类型之间的功能关系。它们聚集在一起形成密集的拓扑结构，对应于传统图聚类算法无法检测到的功能模块。我们开发了Cytoscape 3D，一个Cytoscape插件，用于使用3D谱聚类算法对复合三节点网络图案进行聚类。可用性：通过Cytoscape插件管理器或http://bioinformatics.psb.ugent.be/software/details/CyClus3D.Contact:tom.michoel@frias.uni-freiburg.deSupplementary信息：补充数据可在Bioinformaticsonline获得。
Summary:Network motifs in integrated molecular networks represent functional relationships between distinct data types. They aggregate to form dense topological structures corresponding to functional modules which cannot be detected by traditional graph clustering algorithms. We developed CyClus3D, a Cytoscape plugin for clustering composite three-node network motifs using a 3D spectral clustering algorithm.Availability:Via the Cytoscape plugin manager or http://bioinformatics.psb.ugent.be/software/details/CyClus3D.Contact:tom.michoel@frias.uni-freiburg.deSupplementary Information:Supplementary data are available atBioinformaticsonline.