Predictors of seeking emergency medical help during overdose events in a provincial naloxone distribution programme: a retrospective analysis

Predictors of seeking emergency medical help during overdose events in a provincial naloxone distribution programme: a retrospective analysis
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DOI:
10.1136/bmjopen-2016-011224
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发表时间:
2016-01-01
期刊:
影响因子:
2.9
通讯作者:
Buxton, Jane A.
Buxton, Jane A.
中科院分区:
医学3区
文献类型:
--
作者:
Ambrose, Graham;Amlani, Ashraf;Buxton, Jane A.

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目的本研究旨在确定可能与寻求帮助的证人在过量纳洛酮是administration. Set过量事件发生在,并从五个地区卫生当局横跨加拿大不列颠哥伦比亚省,报告的因素。纳洛酮用药过量事件后填写的表格提交给不列颠哥伦比亚省Take Home Naloxone programme.Participants所有182例报告的纳洛酮用药事件,由成年男性和女性报告,发生在2012年8月31日和2015年3月31日之间,被认为是纳入分析。其中,18例被排除:10起事件由过量用药者报告,8起事件的填写表格未注明是否寻求紧急医疗帮助。(拨打911),据与会者报告,结果在164例纳洛酮过量者中,有89例(54.3%)寻求医疗帮助(紧急服务911呼叫)。大多数行政事件发生在私人住宅(50.6%)和街道(23.4%),其中报告的911呼叫率分别为27.5%和81.1%。在多变量分析中,在街道上发生的药物过量(与私人住宅相比)与拨打911的几率较高显著相关(OR=10.68; 95%CI 2.83至51.87; p
Objectives This study sought to identify factors that may be associated with help-seeking by witnesses during overdoses where naloxone is administered.Setting Overdose events occurred in and were reported from the five regional health authorities across British Columbia, Canada. Naloxone administration forms completed following overdose events were submitted to the British Columbia Take Home Naloxone programme.Participants All 182 reported naloxone administration events, reported by adult men and women and occurring between 31 August 2012 and 31 March 2015, were considered for inclusion in the analysis. Of these, 18 were excluded: 10 events which were reported by the person who overdosed, and 8 events for which completed forms did not indicate whether or not emergency medical help was sought.Primary and secondary outcome measures Seeking emergency medical help (calling 911), as reported by participants, was the sole outcome measure of this analysis.Results Medical help was sought (emergency services911 called) in 89 (54.3%) of 164 overdoses where naloxone was administered. The majority of administration events occurred in private residences (50.6%) and on the street (23.4%), where reported rates of calling 911 were 27.5% and 81.1%, respectively. Overdoses occurring on the street (compared to private residence) were significantly associated with higher odds of calling 911 in multivariate analysis (OR=10.68; 95% CI 2.83 to 51.87; p