CLINICAL EXPERIENCE WITH YOLK SAC TUMORS AND TERATOMA IN CHILDREN

CLINICAL EXPERIENCE WITH YOLK SAC TUMORS AND TERATOMA IN CHILDREN
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儿童卵黄囊肿瘤和畸胎瘤的临床经验

DOI:
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发表时间:
1994
影响因子:
2.6
通讯作者:
O. Yoshida
O. Yoshida
中科院分区:
医学3区
文献类型:
--
作者:
A. Terai;M. Kawakita;O. Yoshida

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1971年至1993年间,京都大学医学部泌尿外科收治了12例睾丸生殖细胞肿瘤患儿。卵黄囊肿瘤7例,成熟畸胎瘤5例。7例卵黄囊肿瘤中,6例为I期,1例为III期。I期肿瘤行高位切除5例,高位切除加腹膜后淋巴结清扫术1例。6例中,4例单纯手术治愈,2例发生肺转移。其中一人经开胸和化疗抢救,另一人因肿瘤死亡。III期患者肿瘤体积较大,扩散至肺部和腹膜后,但经化疗后切除残留肿块似乎已痊愈,但随访仍不足(14个月)。7例患者中有6例(85.7%)在确诊后13个月至21年内存活。5例成熟畸胎瘤患者接受了高位切除术或最近的摘除手术,术后4个月至22年全部存活。
Between 1971 and 1993, 12 children with testicular germ cell tumors were treated at the Department of Urology, Faculty of Medicine, Kyoto University. Seven patients had yolk sac tumors and 5 had mature teratoma. Of the 7 patients with yolk sac tumors, 6 had stage I and 1 had stage III tumors. Initial management of the stage I tumors consisted of high orchiectomy in 5 patients and high orchiectomy plus retroperitoneal lymph node dissection in 1 patient. Of these 6 patients, 4 were cured by surgery alone but lung metastases developed in the other 2 patients. One of them was salvaged with thoracotomy and chemotherapy but the other died of tumor. The patient with stage III tumor had bulky tumor spread to lung and retroperitoneum, but seems to have been cured by chemotherapy followed by resection of the residual mass although follow‐up is still inadequate (14 months). Six of the 7 patients (85.7%) are alive 13 months to 21 years after diagnosis. Five patients with mature teratoma were treated by high orchiectomy or, more recently, enucleation and all are alive 4 months to 22 years after surgery.
圣裘德儿童研究医院在治疗儿童睾丸肿瘤方面拥有二十年的经验。
DOI: 10.1016/s0022-3468(89)80718-3
发表时间: 1989
影响因子: 2.4
作者:
Fernandes,ET;Etcubanas,E;Rao,BN;Kumar,AP;Thompson,EI;Jenkins,JJ
通讯作者: Jenkins,JJ
DOI: 10.1016/s0022-5347(17)44307-2
发表时间: 1987
期刊: The Journal of urology
影响因子: --
作者:
Griffin,GC;RaneyJr,RB;Snyder,HM;Duckett,J;D'Angio,GJ
通讯作者: D'Angio,GJ