DERMATOMYOSITIS-LIKE MUSCLE PATHOLOGY IN PATIENTS WITH CHRONIC GRAFT-VERSUS-HOST DISEASE
DERMATOMYOSITIS-LIKE MUSCLE PATHOLOGY IN PATIENTS WITH CHRONIC GRAFT-VERSUS-HOST DISEASE
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DOI：
10.1002/mus.21353
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发表时间：
2009-10-01
期刊：
影响因子：
3.4
通讯作者：
Amato, Anthony A.
中科院分区：
文献类型：
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作者：
Allen, Jeffrey A.;Greenberg, Steven A.;Amato, Anthony A.
肌炎是造血干细胞移植(HSCT)后慢性移植物抗宿主病(CGVHD)的罕见并发症。据报道，几乎所有这类患者都患有多发性肌炎(PM)。我们描述了3例同种异体造血干细胞移植后发生肌病的cGVHD患者的临床、病理和分子研究。在每个病例中，皮肌炎(DM)的病理组织学特征-束周萎缩都被观察到。肌肉神经40：643-647,2009
Myositis is a rare complication of chronic graft-versus-host disease (cGVHD) following hematopoietic stem cell transplantation (HSCT). Almost all such patients have been reported to have polymyositis (PM). We describe clinical, pathologic, and molecular studies of 3 patients with cGVHD following allogeneic HSCT who developed myopathy. In each case, perifascicular atrophy, the pathognomonic histologic feature of dermatomyositis (DM), was observed. Muscle Nerve 40: 643-647, 2009