Magnetic resonance and cranial ultrasound characteristics of periventricular white matter abnormalities in newborn infants
Magnetic resonance and cranial ultrasound characteristics of periventricular white matter abnormalities in newborn infants
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DOI：
10.1053/crad.2001.0754
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发表时间：
2001-08-01
影响因子：
2.6
通讯作者：
Levene, MI
中科院分区：
文献类型：
--
作者：
Childs, AM;Cornette, L;Levene, MI
目的：为了表征异常的范围内的脑室周围白色物质（PVWM）在一个队列中的新生儿使用磁共振（MR）脑成像和比较局灶性MR异常与颅超声（CUS）findings.METHODS：回顾性研究MR脑和CUS的结果出生在18个月期间1998-1999年的婴儿。通过MR确定PVWM异常，并使用分级量表通过大小、数量和分布表征局灶性病变。对应CUS的调查结果进行了assessed.Results：175 MR检查对应n = 105早产儿，（中位数GA 28，范围23-36周）和n = 25足月儿（中位数GA 39，范围37-42周）进行了PVWM异常分析。在早产儿组中，MR显示PVWM正常（n = 76），PVWM中信号强度改变（ST）的局灶性区域（n = 26）和静脉梗死（n = 3）。在足月组中，MR显示PVWM正常n = 15，PVWM中SI改变的局灶性区域n = 4，PVWM水肿n = 2和大脑中动脉梗死n = 4。所有MR正常的婴儿均具有正常的CUS结果。仅10/30例MR检出的PVWM SI局灶性异常与CUS异常一致。结论：在显示新生儿PVWM局灶性病变的存在和范围方面，MR比CUS敏感得多。只有囊性PVWM病变的两种影像学检查之间的对应关系令人满意。(C)2001年皇家放射科医师学院。
OBJECTIVE: To characterize the range of abnormalities within the periventricular white matter (PVWM) in a cohort of newborns using magnetic resonance (MR) brain imaging and to compare the focal MR abnormalities with the cranial ultrasound (CUS) findings.METHODS: Retrospective study of MR brain and CUS findings of infants born in the 18-month period 1998-1999. PVWM abnormalities were identified by MR and focal lesions were characterized by size, number and distribution using a grading scale. Correspondence with CUS findings was assessed.RESULTS: 175 MR examinations corresponding to n = 105 preterm infants, (median GA 28, range 23-36 weeks) and n = 25 term infants (median GA 39, range 37-42 weeks) were analysed for PVWM abnormalities. In the preterm group, MR demonstrated a normal PVWM in n = 76, focal areas of altered signal intensity (ST) in PVWM in n = 26 and venous infarction in n = 3. In the term group, MR demonstrated a normal PVWM in n = 15, focal areas of altered SI in PVWM in n = 4, oedematous PVWM in it = 2 and a middle cerebral artery infarction in n = 4. All infants with normal MR had normal CUS findings. A focal PVWM SI abnormality detectable on MR corresponded with an abnormality on CUS in only n = 10/30.CONCLUSIONS: MR appears considerably more sensitive than CUS in demonstrating the existence and extent of focal PVWM lesions in newborn infants. Satisfactory correspondence between the two imaging investigations is obtained only for cystic PVWM lesions. (C) 2001 The Royal College of Radiologists.