Effect of a single dose of primaquine on a Thai strain of Plasmodium falciparum.
Effect of a single dose of primaquine on a Thai strain of Plasmodium falciparum.
复制标题
单剂量伯氨喹对泰国恶性疟原虫株的影响。
DOI:
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发表时间:
1980
期刊:
影响因子:
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通讯作者:
T. Harinasuta
中科院分区:
文献类型:
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作者:
Y. Chomcharn;K. Surathin;D. Bunnag;S. Sucharit;T. Harinasuta
A single dose of 45 mg of primaquine base was effective in the elimination of gametocytes of the possibly chloroquine-resistant P. falciparum in Thailand. The gametocyte counts decreased markedly within 3.5 days showing significantly difference from the control in which mostly gametocytes still remain within 11.4 days. The development of the gametocytes in A. dirus was not observed after treatment. Primaquine can be used as gametocytocide and sporontocide for falciparum malaria in Thailand if the drug is administered when matured gametocytes appeared in the peripheral blood.