EEG source reconstruction reveals frontal-parietal dynamics of spatial conflict processing.
EEG source reconstruction reveals frontal-parietal dynamics of spatial conflict processing.
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DOI：
10.1371/journal.pone.0057293
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Ridderinkhof KR
中科院分区：
文献类型：
--
作者：
Cohen MX;Ridderinkhof KR
认知控制需要抑制分散注意力的信息，以便专注于与任务相关的信息。我们通过时频线性约束最小方差波束形成应用EEG源重建来帮助阐明空间冲突处理中涉及的神经机制。人类受试者进行了西蒙任务，其中的冲突引起的空间位置和响应手之间的不一致。我们发现早期（刺激后约200 ms）的刺激对侧顶叶γ（30 - 50 Hz）的冲突调制，其次是后来的α波段（8 - 12 Hz）的冲突调制，这表明早期检测到的空间冲突和抑制的空间位置处理。通过θ（4 - 8 Hz），α和γ功率的交叉频率耦合评估的区域间连接分析显示，冲突引起的皮层网络相互作用的变化：一致性试验（相对于不一致性试验）有更强的额叶θ和刺激-逆半场顶叶α/γ功率之间的耦合，而不一致性试验增加了内侧额叶和外侧额叶区域之间的θ耦合。这些发现揭示了空间冲突处理的大规模网络动力学，以及这些网络是如何通过振荡相互作用形成的。
Cognitive control requires the suppression of distracting information in order to focus on task-relevant information. We applied EEG source reconstruction via time-frequency linear constrained minimum variance beamforming to help elucidate the neural mechanisms involved in spatial conflict processing. Human subjects performed a Simon task, in which conflict was induced by incongruence between spatial location and response hand. We found an early (∼200 ms post-stimulus) conflict modulation in stimulus-contralateral parietal gamma (30–50 Hz), followed by a later alpha-band (8–12 Hz) conflict modulation, suggesting an early detection of spatial conflict and inhibition of spatial location processing. Inter-regional connectivity analyses assessed via cross-frequency coupling of theta (4–8 Hz), alpha, and gamma power revealed conflict-induced shifts in cortical network interactions: Congruent trials (relative to incongruent trials) had stronger coupling between frontal theta and stimulus-contrahemifield parietal alpha/gamma power, whereas incongruent trials had increased theta coupling between medial frontal and lateral frontal regions. These findings shed new light into the large-scale network dynamics of spatial conflict processing, and how those networks are shaped by oscillatory interactions.