A systematic review of dropout from treatment in outpatients with anorexia nervosa
A systematic review of dropout from treatment in outpatients with anorexia nervosa
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DOI：
10.1002/eat.20956
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发表时间：
2012-07-01
影响因子：
5.5
通讯作者：
Schmidt, Ulrike
中科院分区：
文献类型：
--
作者：
DeJong, Hannah;Broadbent, Hannah;Schmidt, Ulrike
目的：治疗中途退出对患者、临床医生和研究人员有着严重的影响。本研究的目的是检查神经性厌食症（AN）门诊治疗的辍学率，并严格检查辍学的各种定义。方法：进行系统评价，包括药物和心理干预。考虑PubMed、Web of Science和科克伦图书馆中的所有文章，并根据先验纳入/排除标准进行筛选。研究中检查了治疗结果与脱落率之间的关系。结果：确定了19项相关研究，退出率从4.8%（家庭治疗）到100%（饮食建议）不等。在大多数情况下，辍学率在20 - 40%之间。辍学的定义差别很大。一个显着的负相关性之间的脱落率和体重指数（BMI）在1年，但这并不保持显着时，在基线BMI的差异考虑在内。讨论：AN治疗的高辍学率对恢复，研究和新治疗方法的开发具有严重影响。提出了一个建议的报告结构，目的是提高辍学报告的一致性，并促进对这一现象的更好理解。(c)出版社：Wiley Periodicals，Inc. (Int J Eat Disord 2011）
OBJECTIVE: Dropout from treatment has serious implications for patients, clinicians, and researchers. The aim of this study was to examine rates of dropout from outpatient treatment for anorexia nervosa (AN) and critically examine the various definitions of dropout used. METHOD: A systematic review was conducted, including pharmacological and psychological interventions. All articles in PubMed, Web of Science, and the Cochrane Library were considered, and screened against a priori inclusion/exclusion criteria. Relationships between treatment outcome and dropout rate were examined across studies. RESULTS: Nineteen relevant studies were identified, with dropout rates ranging from 4.8% (family therapy) to 100% (dietary advice). In most cases, dropout was in the range of 2040%. Definitions of dropout used varied widely. A significant negative correlation was found between rate of dropout and body mass index (BMI) at 1 year, but this did not remain significant when differences in BMI at baseline were taken into account. DISCUSSION: High rates of dropout from treatment for AN have serious implications for recovery, research, and the development of new treatments. A suggested reporting structure is proposed, with the aim of increasing the consistency of dropout reporting and facilitating greater understanding of this phenomenon. (c) 2011 by Wiley Periodicals, Inc. (Int J Eat Disord 2011)