Role of blood flow on RF exposure induced skin temperature elevations in rabbit ears
Role of blood flow on RF exposure induced skin temperature elevations in rabbit ears
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DOI：
10.1002/bem.20286
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发表时间：
2007-04
影响因子：
1.9
通讯作者：
F. Jia;A. Ushiyama;H. Masuda;G. Lawlor;C. Ohkubo
中科院分区：
文献类型：
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作者：
F. Jia;A. Ushiyama;H. Masuda;G. Lawlor;C. Ohkubo
在这项体内研究中，我们测量了兔耳廓的局部温度变化，这是由射频 (RF) 暴露 20 分钟引起的，局部 SAR 水平为 0（假暴露）、2.3、10.0 和 34.3 W/kg，超过 1.0 g 兔耳组织。射频暴露对皮肤温度的影响是在正常血流和耳内无血流的情况下测量的。结果表明：（1）生理血流明显改变了射频引起的耳廓温度升高，因为血流即使在 34.3 W/kg 时也能显着抑制温度升高； (2)在正常血流条件下，2.3和10.0 W/kg的暴露，接近公众现有的安全限值(2 W/kg)和职业暴露(10 W/kg)，不会引起兔耳明显的温度升高。然而，2.3 W/kg 在无血流条件下会引起局部皮肤温度升高。我们的结果表明，在将建模数据外推到活体动物时，应考虑血流的生理效应，并且在解释不包括血流的建模研究结果时需要特别谨慎。生物电磁学 28:163–172, 2007。© 2006 Wiley‐Liss, Inc.
In this in vivo study, we measured local temperature changes in rabbit pinnae, which were evoked by radiofrequency (RF) exposure for 20 min at localized SAR levels of 0 (sham exposure), 2.3, 10.0, and 34.3 W/kg over 1.0 g rabbit ear tissue. The effects of RF exposures on skin temperature were measured under normal blood flow and without blood flow in the ear. The results showed: (1) physiological blood flow clearly modified RF induced thermal elevation in the pinna as blood flow significantly suppressed temperature increases even at 34.3 W/kg; (2) under normal blood flow conditions, exposures at 2.3 and 10.0 W/kg, approximating existing safety limits for the general public (2 W/kg) and occupational exposure (10 W/kg), did not induce significant temperature rises in the rabbit ear. However, 2.3 W/kg induced local skin temperature elevation under no blood flow conditions. Our results demonstrate that the physiological effects of blood flow should be considered when extrapolating modeling data to living animals, and particular caution is needed when interpreting the results of modeling studies that do not include blood flow. Bioelectromagnetics 28:163–172, 2007. © 2006 Wiley‐Liss, Inc.