ANALYSIS OF DATA ON DRUG RELEASE FROM EMULSIONS .2. PYRIDINE RELEASE FROM WATER-IN-OIL EMULSIONS AS A FUNCTION OF PH
ANALYSIS OF DATA ON DRUG RELEASE FROM EMULSIONS .2. PYRIDINE RELEASE FROM WATER-IN-OIL EMULSIONS AS A FUNCTION OF PH
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DOI:
10.1002/jps.2600570117
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发表时间:
1968-01-01
影响因子:
3.8
通讯作者:
HIGUCHI, WI
中科院分区:
文献类型:
--
作者:
KOIZUMI, T;HIGUCHI, WI
The practically important case of the release from an amine—amine hydrochloride solute mixture in a water-in-oil emulsion into an aqueous sink has been studied experimentally and theoretically. All of the parameters entering into the theory have been independently measured and put into the theory. The theoretically predicted release behavior was then determined employing the IBM 7090 computer. These results were then compared to the experimental data obtained over a wide range of conditions. The agreement between the experiments and the physical model was extremely good. These procedures should have extensive application in the future when complex solute—solute, solute—solvent, and solvent—solvent interactions are involved.