COVID-19 vaccine uptake and hesitancy in Chinese patients with asthma
COVID-19 vaccine uptake and hesitancy in Chinese patients with asthma
复制标题
中国哮喘患者对 COVID-19 疫苗的接种和犹豫
作者：
Chun Chang;Xiaoqin Zhang;Yu Feng;Rong;Lina Sun;Ying Liang;Xiaofang Liu;Yanliang Ma;Jie Song;Pingchao Xiang;Er;Liang Chen;Yan;Kewu Huang;Wen Wang;Yahong Chen;Yongchang Sun
摘要目的哮喘患者和医生对疫苗接种都存在犹豫，这可能导致疫苗接种率降低。这项工作的目的是调查北京哮喘患者的疫苗接种率、不良反应以及与疫苗接受和对COVID-19疫苗接种犹豫不决相关的因素。方法对2021年12月至2022年4月连续招募的哮喘患者进行多中心、横断面面对面调查。调查内容包括哮喘状况、COVID-19疫苗接种和不良反应，以及对COVID-19疫苗接种的知识和态度。结果共纳入261例患者。于研究期间，COVID-19疫苗接种率为73. 6%，而中国一般人群的接种率为87. 64%。目前正在工作、过去曾接种过其他疫苗、对其他疫苗没有不良反应的患者，COVID-19疫苗接种率较高。患者认为家人和同事的疫苗接种对其接种疫苗的决定产生了积极影响，更有可能接种COVID-19疫苗。在哮喘监测不力和使用生物疗法的人群中，COVID-19疫苗接种率较低。COVID-19疫苗在哮喘患者中的不良反应与普通人群相似。结论我国哮喘患者COVID-19疫苗接种率低于一般人群。应采取积极措施控制哮喘，并提高这些患者的疫苗接种率。
Abstract Objective Both patients and physicians may be hesitant toward vaccination in patients with asthma, which may result in lower vaccine uptake. The aim of this work was to investigate the vaccination rate, the adverse reactions, as well as the factors associated with vaccine acceptance and hesitancy toward COVID-19 vaccination among asthmatic patients in Beijing. Methods A multi-center, cross-sectional face-to-face survey was conducted in patients with asthma consecutively recruited from December 2021 to April 2022. The survey included asthma status, COVID-19 vaccine uptake and adverse reactions, and knowledge of and attitude toward COVID-19 vaccination. Results A total of 261 patients were enrolled. The rate of COVID-19 vaccination during the study period was 73.6%, as compared to 87.64% in the general population in China. Patients who were currently working, had received other vaccines in the past, and had had no adverse reactions to other vaccines, showed a higher rate of COVID-19 vaccination. Patients believing that the vaccination of family members and colleagues had a positive impact on their decision to get vaccinated, were more likely to get the COVID-19 vaccines. The COVID-19 vaccination rate was lower in those with poorly monitored asthma and those using biologic therapies. The adverse effects of COVID-19 vaccines in asthmatic patients were similar to those in the general population. Conclusion The COVID-19 vaccination rate in asthmatic patients was lower than the general population in China. Active measures should be taken to control asthma and increase vaccination rates in these patients.
IL-5、IL-6 和 IL-10 在针对 Friend 逆转录病毒（鼠白血病病毒）感染的初级免疫反应和疫苗引发的免疫反应中的作用。
DOI：
10.1099/0022-1317-82-6-1349
发表时间：
2001
期刊：
The Journal of general virology
影响因子：
--
作者：
Strestik,BD;Olbrich,AR;Hasenkrug,KJ;Dittmer,U
通讯作者：
Dittmer,U