Room air challenge predicts duration of supplemental respiratory support for infants with bronchopulmonary dysplasia.
Room air challenge predicts duration of supplemental respiratory support for infants with bronchopulmonary dysplasia.
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DOI:
10.1038/s41372-021-00958-2
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发表时间:
2021-04
期刊:
影响因子:
--
通讯作者:
Lagatta J
中科院分区:
文献类型:
--
作者:
Arora P;Dahlgren A;Dawson S;Leuthner J;Lagatta J
To determine whether a room air challenge (RAC) correlates with duration of respiratory support for infants with bronchopulmonary dysplasia (BPD). Prospective study of preterm infants with BPD from 2015–2018. Infants receiving ≤2 liters flow at 36 weeks post-menstrual age (PMA) underwent RAC. Cox regression was used to adjust the duration of respiratory support after 36 weeks PMA for significant covariates. Of 161 infants with BPD, 91 were eligible for RAC; 51 passed and 40 failed. Infants who failed RAC had longer respiratory support after 36 weeks PMA than infants who passed (median 19 weeks (IQR 15–33) versus 2 weeks (IQR 1–8, p<0.001)), which persisted after multivariable adjustment (hazard ratio −1.42, 95% CI −1.94 to −0.91, p<0.001). Infants failing RAC also had more frequent and longer duration of home oxygen use. RAC may help provide anticipatory guidance regarding duration of respiratory support for infants with BPD.
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DOI:
10.1056/nejmoa0911781
发表时间:
2010-05-27
期刊:
The New England journal of medicine
影响因子:
--
作者:
SUPPORT Study Group of the Eunice Kennedy Shriver NICHD Neonatal Research Network;Carlo WA;Finer NN;Walsh MC;Rich W;Gantz MG;Laptook AR;Yoder BA;Faix RG;Das A;Poole WK;Schibler K;Newman NS;Ambalavanan N;Frantz ID 3rd;Piazza AJ;Sánchez PJ;Morris BH;Laroia N;Phelps DL;Poindexter BB;Cotten CM;Van Meurs KP;Duara S;Narendran V;Sood BG;O'Shea TM;Bell EF;Ehrenkranz RA;Watterberg KL;Higgins RD
通讯作者:
Higgins RD
影响因子:
8.3
作者:
Poindexter, Brenda B.;Feng, Rui;Jobe, Alan H.
通讯作者:
Jobe, Alan H.
影响因子:
5.1
作者:
Ellsbury, DL;Acarregui, MJ;Klein, JM
通讯作者:
Klein, JM
影响因子:
158.5
作者:
Askie, LM;Henderson-Smart, DJ;Simpson, JM
通讯作者:
Simpson, JM
影响因子:
5.1
作者:
Lagatta, Joanne;Clark, Reese;Spitzer, Alan
通讯作者:
Spitzer, Alan