On the coupling relation between action potential and mechanical response during repetitive stimulation in frog sartorius muscle.
On the coupling relation between action potential and mechanical response during repetitive stimulation in frog sartorius muscle.
复制标题
青蛙缝匠肌重复刺激时动作电位与机械反应的耦合关系。
DOI：
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发表时间：
1962
期刊：
影响因子：
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通讯作者：
Y. Nakayama
中科院分区：
文献类型：
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作者：
H. Mashima;M. Matsumura;Y. Nakayama
1.以青蛙缝匠肌为研究对象，研究了重复刺激时动作电位与机械反应之间的耦合关系。分割法得到的峰高降低的过程与细胞内记录的过程一致。重复刺激时峰高与峰张力的耦合效率在阶梯现象时先提高后逐渐降低。疲劳、较高的刺激频率和较大的负荷导致了耦合过程的缺失，尤其是机械力-化学过程。在较高的温度下，单次刺激的耦合效率降低，而重复刺激的阶梯现象周期明显延长，速度加快。穗高下降的速度变慢了很多。重复刺激时，负后电位高度或峰时程与峰值张力的相关性较差。当通过神经以2c/s的速度刺激肌肉时，在超过300次刺激的范围内观察到传递性疲劳。讨论了作为收缩激活过程和收缩能量动员过程的复合体的机电耦合。
1. The coupling relation between action potential and mechanical response during repetitive stimulation was investigated using the sartorius muscle of the frog.2. The course of decrease in spike height obtained by partition method coincided with that by intracellular recording.3. The coupling efficiency between spike height and peak tension during repetitive stimulation was improved at first during staircase phenomenon and then it decreased progressively.4. Fatigue, higher stimulating frequency, and heavy load resulted in a deficiency of coupling process, especially the mechano-chemical process.5. At higher temperature, the coupling efficiency for single stimulus was decreased, but for repetitive stimulation the period of staircase phenomenon was greatly prolonged and the rate. of decrease in spike height became much slower.6. The height of negative after-potential or the spike duration showed a poor correlation with peak tension during repetitive stimulation.7. When the muscle was stimulated at 2c/sec through nerve, transmission fatigue was observed in the range beyond 300 stimuli.8. The electro-mechanical coupling, as the complex of the activation process for contraction and the energy mobilizing process in contraction, was discussed.