Comorbidity of substance use disorders with mood and anxiety disorders: Results of the International Consortium in Psychiatric Epidemiology
Comorbidity of substance use disorders with mood and anxiety disorders: Results of the International Consortium in Psychiatric Epidemiology
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DOI：
10.1016/s0306-4603(98)00076-8
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发表时间：
1998-11-01
影响因子：
4.4
通讯作者：
Kessler, RC
中科院分区：
文献类型：
--
作者：
Merikangas, KR;Mehta, RL;Kessler, RC
本文报告了参加国际精神病学联合会的六项研究中物质使用与精神疾病共病模式的跨国调查结果。总的来说，情绪和焦虑障碍以及行为和反社会人格障碍与物质障碍在所有方面都有很强的联系。研究结果还表明，作为物质使用类别（使用、问题、依赖）的一个函数，共病的程度是连续的，同时，共病疾病的数量与物质使用障碍严重程度的增加之间存在直接关系（这在药物方面尤为明显）。最后，虽然情绪障碍与物质障碍之间没有特定的发病时间模式，但在所有国家，焦虑障碍的发病更有可能先于物质障碍。这些结果说明了跨国数据对理解精神病理和物质使用障碍的模式和风险因素的贡献。1998爱思唯尔科学有限公司
This article reports the results of a cross-national investigation of patterns of comorbidity between substance use and psychiatric disorders in six studies participating in the International Consortium in Psychiatric Epidemiology. In general, there was a strong association between mood and anxiety disorders as well as conduct and antisocial personality disorder with substance disorders at all sites. The results also suggest that there is a continuum in the magnitude of comorbidity as a function of the spectrum of substance use category (use, problems, dependence), as well as a direct relationship between the number of comorbid disorders and increasing levels of severity of substance use disorders (which was particularly pronounced for drugs). Finally, whereas there was no specific temporal pattern of onset for mood disorders in relation to substance disorders, the onset of anxiety disorders was more likely to precede that of substance disorders in all countries. These results illustrate the contribution of cross-national data to understanding the patterns and risk factors for psychopathology and substance use disorders. (C) 1998 Elsevier Science Ltd.