THE EPIDEMIOLOGY OF GIANT-CELL ARTERITIS INCLUDING TEMPORAL ARTERITIS AND POLYMYALGIA RHEUMATICA - INCIDENCES OF DIFFERENT CLINICAL PRESENTATIONS AND EYE COMPLICATIONS
THE EPIDEMIOLOGY OF GIANT-CELL ARTERITIS INCLUDING TEMPORAL ARTERITIS AND POLYMYALGIA RHEUMATICA - INCIDENCES OF DIFFERENT CLINICAL PRESENTATIONS AND EYE COMPLICATIONS
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DOI：
10.1002/art.1780240706
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发表时间：
1981-01-01
影响因子：
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通讯作者：
MALMVALL, BE
中科院分区：
文献类型：
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作者：
BENGTSSON, BA;MALMVALL, BE
在瑞典哥德堡的3年期间，诊断出126例巨细胞动脉炎（GCA）。74例（59%）颞动脉活检发现动脉炎的组织学证据。计算GCA年总发病率为9.3/10万居民。50岁以上年龄组发病率为28.6/10万。组织学证实的GCA发病率为总人口的5.5/10万。50岁以上年龄组的相应数字为16.8/10万。26例（21%）患者有颞动脉炎的临床表现，23例（18%）有颞动脉炎和风湿性多肌痛（PMR）的合并表现。67例（53%）患者无颞叶症状，10例（8%）患者无症状，仅有一般症状。PMR综合征在患有GCA的女性（79%）中比男性（56%）更常见。在没有肌肉症状的病人组中，男女人数相等。眼部并发症15例（12%）。6例眼部症状为短暂性，9例为永久性视力丧失。其中3例颞动脉活检未发现动脉炎，5例无局限性颞动脉炎的临床体征。
During a period of 3 yr in Goteborg, Sweden, 126 cases of giant cell arteritis (GCA) were diagnosed. Histologic evidence of arteritis was found on temporal artery biopsy in 74 (59%). The total annual incidence of GCA was calculated to be 9.3/100,000 inhabitants. In the age group over 50 yr, the incidence was 28.6/100,000. For histologically proven GCA the incidence was 5.5/100,000 of the total population. The corresponding figure in the age group over 50 yr was 16.8/100,000. Twenty-six patients (21%) had a clinical presentation of temporal arteritis and 23 (18%) had a combined picture of temporal arteritis and polymyalgia rheumatica (PMR). Sixty-seven (53%) had the PMR syndrome without any temporal symptoms and 10 patients (8%) had a silent presentation with only general symptoms. The PMR syndrome was more common among women with GCA (79%) than among men (56%). The group of patients without muscular symptoms contained an equal number of men and women. Eye complications were seen in 15 patients (12%). In 6 the ocular symptoms were transient, while 9 had permanent loss of vision. In 3 of these patients, temporal artery biopsy revealed no evidence of arteritis, and 5 had no clinical signs of localized temporal arteritis.