Allograft colonization and infections with Pseudomonas in cystic fibrosis lung transplant recipients
Allograft colonization and infections with Pseudomonas in cystic fibrosis lung transplant recipients
复制标题
DOI：
10.1378/chest.113.5.1235
复制
发表时间：
1998-05-01
期刊：
影响因子：
9.6
通讯作者：
Dauber, JH
中科院分区：
文献类型：
--
作者：
Nunley, DR;Grgurich, W;Dauber, JH
目的：评估与其他终末期肺病患者相比，肺移植囊性纤维化（CF）患者的假单胞菌感染、定植和炎症发生率。设计：回顾性分析。设置：大学医学中心移植服务。患者：所有CF和慢性假单胞菌感染患者（n=62）和非脓毒性终末期肺病患者（n=52）结果：50例肺移植术后并发CF的受者均存活超过术后第15天（POD），并接受了支气管镜检查和BAL检查。44例CF肺移植受者中位POD 15时从同种异体移植物中分离出假单胞菌，而21例非CF肺移植受者中位POD 15时分离出假单胞菌（p
Objective: To assess the incidence of pseudomonal infection, colonization, and inflammation in the allograft of lung transplant recipients with cystic fibrosis (CF) as compared with recipients with other end-stage lung disease.Design: Retrospective review.Setting: University medical center transplant service.Patients: All patients with CF and chronic pseudomonal infection (n=62) and patients with nonseptic end-stage lung disease (n=52) receiving a double lung transplant between October 1983 and March 1996.Results: Fifty lung transplant recipients with CF survived beyond postoperative day (POD) 15 and were subject to sequential bronchoscopy with BAL. Forty-four CF lung transplant recipients had Pseudomonas isolated from the allograft by median POD 15 as compared with 21 non-CF lung transplant recipients (p