Acquired immunodeficiency syndrome. Clinicopathologic study of 56 autopsies.
Acquired immunodeficiency syndrome. Clinicopathologic study of 56 autopsies.
复制标题
获得性免疫缺陷综合症。
DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
Schinella Ra
中科院分区：
文献类型：
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作者：
Niedt Gw;Schinella Ra
我们研究了56名在纽约大学医学中心接受尸检的获得性免疫缺陷综合征患者。我们发现了几个在以前的系列中没有描述或强调的实体。这些建议如下：（1）3例坏死性动脉炎伴巨细胞病毒包涵体;（2）95%的卡波西肉瘤病例中存在播散;（3）卡波西肉瘤不寻常的临床和组织学表现给临床医生和病理学家带来诊断困难;（4）严重的非分枝杆菌感染的发生率非常高。此外，以前的尸检研究对获得性免疫缺陷综合征中播散性念珠菌病、噬血细胞症和严重肾上腺坏死的发生率等问题存在分歧。除一项研究外，所有这些研究均涉及10至12例病例。我们对56个案例的研究有助于解决这些分歧。
: We studied 56 patients with acquired immunodeficiency syndrome who underwent autopsy at the New York University Medical Center. We uncovered several entities that were not previously described or emphasized in prior series. These were as follows: (1) three cases of necrotizing arteritis with cytomegalovirus inclusions; (2) dissemination in 95% of cases of Kaposi's sarcoma; (3) unusual clinical and histologic presentations of Kaposi's sarcoma presenting diagnostic difficulties for both clinicians and pathologists; and (4) a very high incidence of serious nonmycobacterial infections. In addition, previous autopsy studies have disagreed over such matters as the incidence of disseminated candidiasis, hemophagocytosis, and severe adrenal necrosis in acquired immunodeficiency syndrome. All of these studies, except one, involved ten to 12 cases each. Our study of 56 cases helps to resolve these disagreements.