Interlaced spectrally encoded confocal scanning laser ophthalmoscopy and spectral domain optical coherence tomography.
Interlaced spectrally encoded confocal scanning laser ophthalmoscopy and spectral domain optical coherence tomography.
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DOI：
10.1364/boe.1.000431
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发表时间：
2010-08-02
影响因子：
3.4
通讯作者：
Izatt JA
中科院分区：
文献类型：
--
作者：
Tao YK;Farsiu S;Izatt JA
扫描激光检眼镜（SLO）和光谱域光学相干断层扫描（SDOCT）已成为眼科的重要临床诊断工具，允许视频速率的非侵入性的正面和深度分辨可视化的视网膜结构。将SLO和OCT两者联合收割机组合作为图像跟踪手段的当前一代多模态成像系统在其硬件实现中仍然是复杂的。在这里，我们结合联合收割机的光谱编码共焦扫描激光检眼镜（SECSLO）与眼科SDOCT系统。这种隔行扫描SECSLO-SDOCT系统的新颖实现允许视频速率SLO眼底图像与高分辨率SDOCT B扫描交替采集，作为图像瞄准、引导和配准以及运动跟踪的手段。该系统在SLO和OCT之间共享照明源、检测系统和扫描光学器件，作为提供简单的多模态眼科成像系统的方法，该系统可以容易地实现为桌面或手持设备。
Scanning laser ophthalmoscopy (SLO) and spectral domain optical coherence tomography (SDOCT) have become essential clinical diagnostic tools in ophthalmology by allowing for video-rate noninvasive en face and depth-resolved visualization of retinal structure. Current generation multimodal imaging systems that combine both SLO and OCT as a means of image tracking remain complex in their hardware implementations. Here, we combine a spectrally encoded confocal scanning laser ophthalmoscope (SECSLO) with an ophthalmic SDOCT system. This novel implementation of an interlaced SECSLO-SDOCT system allows for video-rate SLO fundus images to be acquired alternately with high-resolution SDOCT B-scans as a means of image aiming, guidance, and registration as well as motion tracking. The system shares the illumination source, detection system, and scanning optics between both SLO and OCT as a method of providing a simple multimodal ophthalmic imaging system that can readily be implemented as a table-top or hand-held device.