Nationwide Incidence of Clinically Diagnosed Central Retinal Artery Occlusion in Korea, 2008 to 2011
Nationwide Incidence of Clinically Diagnosed Central Retinal Artery Occlusion in Korea, 2008 to 2011
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DOI：
10.1016/j.ophtha.2014.04.029
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发表时间：
2014-10-01
期刊：
影响因子：
13.7
通讯作者：
Woo, Se Joon
中科院分区：
文献类型：
--
作者：
Park, Sang Jun;Choi, Nam-Kyong;Woo, Se Joon
目的：目的：明确韩国临床诊断的视网膜中央动脉阻塞（CRAO）的发病率和人口统计学特征。设计：基于全国人群的回顾性研究，使用2007年至2011年韩国国家健康索赔数据库中的数据。参与者：整个韩国人群的数据方法：我们使用国家健康索赔数据库来识别诊断为CRAO的患者。事件案例是指2007年没有与CRAO相关索赔的案例，并在2008年至2011年与CRAO相关的最早索赔中纳入一次。发病病例在诊断前至少有1至4年的无病期。CRAO的平均发病率估计根据整个韩国population.Main结果措施：在韩国的临床诊断的CRAO，包括年龄和性别特异性发病率的人的时间发病率，estimated.Results：共3464例CRAO（59.1%的男性）被确定。研究期间临床诊断CRAO的发生率为1.80/100 000人-年（95%置信区间[CI]，1.74-1.86）。男性和女性的发病率分别为2.15（95%CI，2.05-2.24）和1.47（95%CI，1.39-1.54）/10万人-年（男女比，1.47）。年龄特异性男女比例在30至89岁之间保持不变（范围，1.51-2.10岁）。最高发病率10.08（95% CI，8.80-11.35）/10万人年（80-84岁男性和女性分别为14.65 [95% CI，11.90-17.40]和8.00 [95% CI，6.63-9.37]/100 000人-年）。CRAO的发病率随着年龄的增长呈指数增长，直到第9个十年的life.Conclusions：据我们所知，这是第一个全国性的流行病学研究CRAO在所有年龄段的个人。韩国CRAO的发病率随着年龄的增长呈指数增长，在80至84岁的人群中最高。男性的发病率是女性的1.47倍。(C)2014年由美国眼科学会。
Purpose: To define the incidence and demographics of clinically diagnosed central retinal artery occlusion (CRAO) in Korea.Design: Nationwide population-based retrospective study using data entered into the Korean national health claims database from 2007 to 2011.Participants: Data of the entire Korean population (N = 47 990 761, based on the 2010 census) were analyzed.Methods: We used the national health claims database to identify patients diagnosed with CRAO. Incident cases were those with no claims related to CRAO in 2007 and were included once on the earliest claims related to CRAO in the years 2008 to 2011. Incident cases had a disease-free period before diagnosis of at least 1 to 4 years. The average incidence rate of CRAO was estimated according to the entire Korean population.Main Outcome Measures: The person-time incidence rates of clinically diagnosed CRAO in Korea, including the age-and sex-specific incidence rates, were estimated.Results: A total of 3464 CRAO cases (59.1% men) were identified. The incidence rate of clinically diagnosed CRAO during the study period was 1.80 per 100 000 person-years (95% confidence interval [CI], 1.74-1.86). The incidence rate among men and women was 2.15 (95% CI, 2.05-2.24) and 1.47 (95% CI, 1.39-1.54) per 100 000 person-years (male-to-female ratio, 1.47), respectively. The age-specific male-to-female ratios were constant between the ages of 30 and 89 years (range, 1.51-2.10 years). The highest incidence of 10.08 (95% CI, 8.80-11.35) per 100 000 person-years was observed in those aged 80 to 84 years (14.65 [95% CI, 11.90-17.40] and 8.00 [95% CI, 6.63-9.37] per 100 000 person-years for men and women aged 80-84 years, respectively). The incidence rate of CRAO increased exponentially with age until the 9th decade of life.Conclusions: To our knowledge, this is the first nationwide epidemiologic study of CRAO in individuals of all ages. The incidence rate of CRAO in Korea increased exponentially with increasing age and was highest among those aged 80 to 84 years. Moreover, the incidence rate in men was 1.47 times higher than that in women. (C) 2014 by the American Academy of Ophthalmology.