DIP, the Database of Interacting Proteins:: a research tool for studying cellular networks of protein interactions

DIP, the Database of Interacting Proteins:: a research tool for studying cellular networks of protein interactions
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DOI:
10.1093/nar/30.1.303
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发表时间:
2002-01-01
影响因子:
14.9
通讯作者:
Eisenberg, D
Eisenberg, D
中科院分区:
生物学2区
文献类型:
--
作者:
Xenarios, I;Salwínski, L;Eisenberg, D

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相互作用蛋白质数据库(DIP:http://dip.doe-mbi.ucla.edu)是一个记录实验确定的蛋白质-蛋白质相互作用的数据库。它为科学界提供了一套集成的工具,用于浏览和提取有关蛋白质相互作用网络的信息。截至 2001 年 9 月,DIP 编目了来自超过 80 个生物体的 5900 种蛋白质之间的 11 000 种独特的相互作用;绝大多数来自酵母菌、幽门螺杆菌和人类。已经开发出的工具允许用户分析、可视化并将他们自己的实验数据与 DIP 数据库中提供的有关蛋白质-蛋白质相互作用的信息整合起来。
The Database of Interacting Proteins (DIP: http://dip.doe-mbi.ucla.edu) is a database that documents experimentally determined protein-protein interactions. It provides the scientific community with an integrated set of tools for browsing and extracting information about protein interaction networks. As of September 2001, the DIP catalogs similar to11 000 unique interactions among 5900 proteins from >80 organisms; the vast majority from yeast, Helicobacter pylori and human. Tools have been developed that allow users to analyze, visualize and integrate their own experimental data with the information about protein-protein interactions available in the DIP database.