BLOOD-PRESSURE CONTROL - SPECIAL ROLE OF THE KIDNEYS AND BODY-FLUIDS
BLOOD-PRESSURE CONTROL - SPECIAL ROLE OF THE KIDNEYS AND BODY-FLUIDS
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DOI：
10.1126/science.2063193
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发表时间：
1991-06-28
期刊：
影响因子：
56.9
通讯作者：
GUYTON, AC
中科院分区：
文献类型：
--
作者：
GUYTON, AC
成年人的动脉压每天很少偏离正常值超过10%至15%。为了达到这种恒定性，身体有一个压力控制系统网络。有几种是基于神经受体，在几秒钟内作出反应，以帮助纠正任何异常的压力。这些系统的活动在几分钟内被荷尔蒙控制器激活。在数小时或数天内，诱导肾脏压力控制系统，当压力福尔斯下降时增加体液体积（或当压力上升时减少体积）。这种肾液系统是建立长期压力控制的主要方法。
The arterial pressure of the adult human rarely deviates from normal by more than 10 to 15 percent, during each day. To achieve such constancy, the body has a network of pressure control systems. Several are based on neural receptors that respond within seconds to help correct any abnormal pressure. The activities of these systems are followed within minutes by activation of hormonal controllers. Within hours or days, a kidney pressure control system is induced that increases body fluid volume when the pressure falls (or decreases the volume when the pressure rises). This kidney-fluid system is the dominant method of establishing long-term pressure control.