Readout-segmented Echo-pIanar Imaging Improves the Diagnostic Performance of Diffusion-weighted MR Breast Examinations at 3.0 T
Readout-segmented Echo-pIanar Imaging Improves the Diagnostic Performance of Diffusion-weighted MR Breast Examinations at 3.0 T
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DOI：
10.1148/radiol.12111494
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发表时间：
2012-04-01
期刊：
影响因子：
19.7
通讯作者：
Gruber, Stephan
中科院分区：
文献类型：
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作者：
Bogner, Wolfgang;Pinker-Domenig, Katja;Gruber, Stephan
目的：定性和定量比较基于标准单次回波平面成像和读出分段回波平面成像的弥散加权（DW）磁共振（MR）成像对3.0 t乳腺癌患者的诊断价值。材料和方法：获得机构审查委员会批准并书面知情同意。47例经组织病理学证实的病变纳入本研究。在所有患者中，使用3.0 t MR成像仪进行DW成像，包括单次回波平面成像和具有相似成像参数的读出分段回波平面成像。两名独立的阅读者视觉评估图像质量和病变显著性，并对图像特性（即信噪比、对比度、几何畸变）进行量化。在所有病变（28例恶性，21例良性）和正常乳腺实质中绘制感兴趣的区域，以研究表观扩散系数（ADC）的差异。诊断准确性根据ADC阈值1.25 x 10(-3) mm(2)/秒计算。结果：每个阅读器发现读数分割的诊断准确率（96%）比单次回波平面成像（90%）更高。读数分段超声平面成像曲线下面积（0.981）显著大于单次超声平面成像（0.867）（P = 0.026）。两种DW成像方法获得的ADC无显著差异。读数分割超声平面成像的病变显著性和图像质量优于单次超声平面成像（P < 0.001）。读出分段回波平面成像将几何畸变减少了三倍。结论：基于读出分割回声平面成像的DW成像通过减少临床高场强磁共振成象器的几何畸变、图像模糊和伪影水平，提供了比单次回声平面成像更高的图像质量和病变显著性。由此可见，读出分割回声平面成像对乳腺良恶性病变的鉴别诊断准确率较高。(c) rsna, 2012
Purpose: To qualitatively and quantitatively compare the diagnostic value of diffusion-weighted (DW) magnetic resonance (MR) imaging based on standard single-shot echo-planar imaging and readout-segmented echo-planar imaging in patients with breast cancer at 3.0 T.Materials and Methods: Institutional review board approval and written informed consent were obtained. Forty-seven patients with 49 histopathologically verified lesions were included in this study. In all patients, DW imaging, with single-shot echo-planar imaging and readout-segmented echo-planar imaging with comparable imaging parameters, was performed with a 3.0-T MR imager. Two independent readers visually assessed image quality and lesion conspicuity, and image properties (ie, signal-to-noise ratio, contrast, geometric distortions) were quantified. Regions of interest were drawn in all lesions (28 malignant, 21 benign) and in the normal breast parenchyma to investigate differences in apparent diffusion coefficient (ADC). Diagnostic accuracy was calculated on the basis of an ADC threshold of 1.25 x 10(-3) mm(2)/sec.Results: Each reader found a higher diagnostic accuracy for readout-segmented (96%) than for single-shot (90%) echo-planar imaging. The area under the curve for readout-segmented echo-planar imaging (0.981) was significantly larger than for single-shot echo-planar imaging (0.867) (P = .026). There was no significant difference in the ADC obtained by using either DW imaging method. Lesion conspicuity and image quality of readout-segmented echo-planar imaging were rated superior to those of single-shot echo-planar imaging (P < .001). Readout-segmented echo-planar imaging reduced geometric distortions by a factor of three.Conclusion: DW imaging based on readout-segmented echo-planar imaging provided significantly higher image quality and lesion conspicuity than single-shot echo-planar imaging by reducing geometric distortions, image blurring, and artifact level with a clinical high-field-strength MR imager. Thereby, readout-segmented echo-planar imaging reached a higher diagnostic accuracy for the differentiation of benign and malignant breast lesions. (C) RSNA, 2012