Blastocystis hominis: an organism in search of a disease.
Blastocystis hominis: an organism in search of a disease.
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人芽囊原虫：寻找疾病的生物体。
DOI：
10.1097/00006454-198908000-00036
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
B. Minshew
中科院分区：
文献类型：
--
作者：
Richard A. Miller;B. Minshew
人胚囊虫是一种常见于人肠道的原生动物。我们对11例连续出现肠炎症状并以人芽胞杆菌为唯一肠道病原体的患者进行了研究，试图确定囊胚增生与临床疾病的关系。在这些患者中，人芽胞杆菌未被认为是肠炎的病原。所有11人的肠道症状都有不同的（通常是非传染性的）解释。症状的缓解与抗原虫治疗或粪便中人原杆菌的消失没有相关性。所有先前将人芽杆菌与人类疾病联系起来的报告都已经过审查，并没有提供令人信服的因果关系证据。人结核菌很少是，如果曾经，人类病原体，并没有针对根除人结核菌的治疗。
Blastocystis hominis is a protozoan organism frequently found in the human intestinal tract. Eleven consecutive patients with symptoms of enteritis and having B. hominis as the sole enteropathogen were studied in an attempt to define the association of blastocystosis with clinical disease. B. hominis could not be implicated as the etiologic agent of enteritis in any of these patients. All eleven had alternative (and usually noninfectious) explanations for their intestinal symptoms. There was no correlation between resolution of symptoms and either antiprotozoal therapy or disappearance of B. hominis from the stools. All prior reports associating B. hominis with human disease have been reviewed and provide no convincing proof of a causal relation. B. hominis is rarely, if ever, a human pathogen, and treatment directed at the eradication of B. hominis is not indicated.