Eliciting a counterfactual sensitivity parameter

Eliciting a counterfactual sensitivity parameter
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DOI:
10.1198/000313007x163213
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发表时间:
2007-02-01
影响因子:
1.8
通讯作者:
Mehrotra, Devan V.
Mehrotra, Devan V.
中科院分区:
数学2区
文献类型:
--
作者:
Shepherd, Bryan E.;Gilbert, Peter B.;Mehrotra, Devan V.

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敏感性分析,即对敏感性参数的每一个范围值进行估计,在因果推理中特别有用,其中估计通常是由于不可检验的假设而确定的。敏感性参数可能有反事实的解释,使其引出特别具有挑战性。本文描述了我们的经验,得出一个反事实敏感性参数,用于分析正在进行的艾滋病毒疫苗试验。我们包括给10位主题专家的说明,我们的8位回应者的选择范围和他们的一些评论,他们的范围应用于早期试验的数据,以及关于反事实引出的一些一般问题的简要讨论。
Sensitivity analyses, wherein estimation is performed for each of a range of values of a sensitivity parameter, are of particular use in causal inference, where estimands often are identified because of untestable assumptions. Sensitivity parameters may have counterfactual interpretations, making their elicitation especially challenging. This article describes our experience eliciting a counterfactual sensitivity parameter to be used in the analysis of an ongoing HIV vaccine trial. We include instructions given to 10 subject-matter experts, the chosen ranges of our eight responders and some of their comments, their ranges applied to data from an earlier trial, and a brief discussion of some general issues regarding counterfactual elicitation.