Neuromuscular Assessments of Form and Function
Neuromuscular Assessments of Form and Function
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形式和功能的神经肌肉评估
DOI：
10.1007/978-1-0716-3315-1_15
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Jones E
中科院分区：
文献类型：
--
作者：
Jones E
流向骨骼肌的血流是输送氧气和营养物质以及清除代谢副产物的重要决定因素，从而促进肌肉健康和收缩功能。反映这一点，随着年龄增长或疾病发生的肌肉血液供应障碍可能会限制功能能力，并对整体健康有害。在临床和研究环境中，已经使用多种方法来测量肌肉血流量，每种方法都有其优点和局限性。广泛使用的超声造影是一种相对简单的微创方法，使用静脉注射微泡直接记录骨骼肌微血管系统中的灌注活动。然而，尽管这项技术相对容易，并且在研究神经肌肉系统时骨骼肌血流信息的明确效用，但目前在这一领域的研究仍然有限。骨骼肌血流量测量方法的发展在神经肌肉研究中有着广泛的应用前景。
Blood flow to skeletal muscles is an important determinant for delivery of oxygen and nutrients and removal of metabolic by-products, thereby facilitating muscle health and contractile function. Reflecting this, impairments in muscle blood supply occurring with advancing age or disease can restrict functional ability and be detrimental to overall health. Multiple methods have been used to measure muscle blood flow in both clinical and research environments, each with advantages and limitations to their use. Extensively used, contrast-enhanced ultrasound is a relatively simple, minimally invasive method using intravenously injected microbubbles to directly record perfusion activity in the skeletal muscle microvasculature. However, despite the relative ease of this technique and the clear utility of information on skeletal muscle blood flow when studying the neuromuscular system, research in this space is currently limited. The development of methodologies for measuring skeletal muscle blood flow has future potential for many applications in neuromuscular research.