Intramolecular benzoallene-;alkyne cycloaddition initiated by site-selective SN2’ reaction of epoxytetracene en route to π-extended pyracylene
Intramolecular benzoallene-;alkyne cycloaddition initiated by site-selective SN2’ reaction of epoxytetracene en route to π-extended pyracylene
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由环氧四苯的位点选择性 SN2 反应引发的分子内苯并联烯-;炔环加成反应生成 π-延伸的吡苯
DOI：
10.1039/c9cc05500b
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
T. Hamura*
中科院分区：
文献类型：
--
作者：
K. Kitamura;K. Asahina;K. Adachi;T. Hamura*
以环氧并四苯为原料，经卤化氢催化的级联反应合成了含苯并丙二烯中间体的卤代苯并茚并四苯。苯并茚并四苯中剩余的两个炔基进一步与降冰片二烯或芳胺通过过渡金属催化的环化反应得到了π-延伸的并吡喃衍生物。
A hydrogen halide promoted cascade reaction of epoxytetracene to afford halo-benzoindenotetracene including a benzoallene intermediate was developed. The remaining two alkynyl groups in benzoindenotetracene were further reacted with norbornadiene or arylamine through transition metal-catalyzed cyclization to give π-extended pyracylene derivatives.