Effects of ascorbic acid, glutathione, thiocyanate, and iodide on antimicrobial activity of acidified nitrite
Effects of ascorbic acid, glutathione, thiocyanate, and iodide on antimicrobial activity of acidified nitrite
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DOI：
10.1128/aac.48.2.655-658.2004
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发表时间：
2004-02-01
影响因子：
4.9
通讯作者：
Leifert, C
中科院分区：
文献类型：
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作者：
Fite, A;Dykhuizen, R;Leifert, C
据推测，膳食中的亚硝酸盐转化为一氧化氮和其他活性氮中间体后会增强胃酸的抗菌活性，从而增强对胃肠道感染的抵抗力。在这项研究中，我们发现还原剂抗坏血酸和谷胱甘肽降低了酸化亚硝酸盐对抗小肠结肠炎耶尔森氏菌（P
It has been hypothesized that dietary nitrite augments the antimicrobial activity of gastric acid after conversion to nitric oxide and other reactive nitrogen intermediates, thus resulting in increased resistance against gastrointestinal infection. In this study, we showed that the reducing agents ascorbic acid and glutathione reduced the activity of acidified nitrite against Yersinia enterocolitica (P