Drop-on-demand printed microfluidics device with sensing electrodes using silver and PDMS reactive inks
Drop-on-demand printed microfluidics device with sensing electrodes using silver and PDMS reactive inks
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DOI：
10.1007/s10404-017-2010-8
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发表时间：
2017-11-01
影响因子：
2.8
通讯作者：
Hildreth, Owen
中科院分区：
文献类型：
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作者：
Mamidanna, Avinash;Lefky, Christopher;Hildreth, Owen
在这项工作中，开发了一种就地固化的聚二甲基硅氧烷 (PDMS) 反应性墨水，并通过打印带有集成电极的完整微流体混合器来测量流体电导率、浓度和混合完整性来证明其实用性。首先，进行参数空间研究以生成一组与按需滴注 (DOD) 印刷约束兼容的 PDMS 油墨和印刷参数。接下来，使用 DOD 印刷的银活性墨水、PDMS 活性墨水和低温聚乙二醇短效墨水制造微流体混合器。最后，使用浓度范围为0.01至1.0 M的NaCl溶液对装置进行校准和测试，结果表明可以准确测量电解质浓度和混合完整性。总体而言，这项工作展示了一套反应性墨水和工艺，可使用低成本墨水和 DOD 打印技术制造复杂的微流体设备。
For this work, a cure-in-place polydimethylsiloxane (PDMS) reactive ink was developed and its utility demonstrated by printing a complete microfluidic mixer with integrated electrodes to measure fluid conductivity, concentration, and mixing completeness. First, a parameter-space investigation was conducted to generate a set of PDMS inks and printing parameters compatible with drop-on-demand (DOD) printing constraints. Next, a microfluidic mixer was fabricated using DOD-printed silver reactive inks, PDMS reactive inks, and a low-temperature polyethylene glycol fugitive ink. Lastly, the device was calibrated and tested using NaCl solutions with concentrations ranging from 0.01 to 1.0 M to show that electrolyte concentration and mixing completeness can be accurately measured. Overall, this work demonstrates a set of reactive inks and processes to fabricate sophisticated microfluidic devices using low-cost inks and DOD printing techniques.