Evolutionary history predicts the stability of cooperation in microbial communities
Evolutionary history predicts the stability of cooperation in microbial communities
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DOI：
10.1038/ncomms3573
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发表时间：
2013-10-01
影响因子：
16.6
通讯作者：
Scheu, Stefan
中科院分区：
文献类型：
--
作者：
Jousset, Alexandre;Eisenhauer, Nico;Scheu, Stefan
合作从根本上有助于地球上生命的成功，但它在不同社区中的持久性仍然是一个谜，因为自私的表型迅速进化并可能传播，直到破坏合作。在这里，我们调查进化历史如何影响多物种社区中叛逃者的出现和传播。我们建立了不同多样性和系统发育相关性的细菌群落，并测量了合作（蛋白水解活性）的投资及其对叛逃者入侵的脆弱性。我们表明，进化关系预测合作的稳定性：遗传多样性的社区迅速入侵自发的信号盲突变体（忽略信号调节合作），而合作是稳定的密切相关的。合作的维持是由对背叛者的拮抗作用控制的：合作者抑制与遗传学相关的背叛者，但不抑制远亲。这种亲属依赖性抑制链接系统发育多样性和进化动力学，从而提供了一个强大的机制预测的持久性合作在自然社区。
Cooperation fundamentally contributes to the success of life on earth, but its persistence in diverse communities remains a riddle, as selfish phenotypes rapidly evolve and may spread until disrupting cooperation. Here we investigate how evolutionary history affects the emergence and spread of defectors in multispecies communities. We set up bacterial communities of varying diversity and phylogenetic relatedness and measure investment into cooperation (proteolytic activity) and their vulnerability to invasion by defectors. We show that evolutionary relationships predict the stability of cooperation: phylogenetically diverse communities are rapidly invaded by spontaneous signal-blind mutants (ignoring signals regulating cooperation), while cooperation is stable in closely related ones. Maintenance of cooperation is controlled by antagonism against defectors: cooperators inhibit phylogenetically related defectors, but not distant ones. This kin-dependent inhibition links phylogenetic diversity and evolutionary dynamics and thus provides a robust mechanistic predictor for the persistence of cooperation in natural communities.