Prevalence of respiratory and hyperreactivity symptoms in relation to levels of criteria air pollutants in Sweden

Prevalence of respiratory and hyperreactivity symptoms in relation to levels of criteria air pollutants in Sweden
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DOI:
10.1093/eurpub/7.3.291
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发表时间:
1997-09-01
影响因子:
4.4
通讯作者:
Wall, S
Wall, S
中科院分区:
医学3区
文献类型:
--
作者:
Forsberg, B;Stjernberg, N;Wall, S

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我们对暴露于低水平空气污染对健康的不利影响的认识仍然不足。早期指标,如呼吸道症状,需要更多的关注。我们利用了这样一个事实,即当相关的暴露和其他决定因素得到很好的控制时,可能的微弱影响可以更容易地被发现。一份邮寄的调查问卷被发送到随机抽样的居民登记为居住在附近的55个位于中心的空气质量监测站在瑞典城镇。共回收问卷6,109份(76%)。采用混杂控制的多变量分析来研究不同水平的标准污染物对症状患病率的影响。二氧化氮和二氧化硫的半年值范围分别为9-32和2-16 μ g/m3。Logistic回归分析显示,在接触最多的人中,呼吸系统疾病的风险较高,如咳嗽、咽喉刺激和鼻子刺激,这种关联在妇女接触二氧化氮时最为明显。空气污染暴露的影响目前无法进行医学评估,但它们仍然很有趣,因为它们被发现在通常被认为是安全的常见水平内。
Our knowledge of the adverse health effects from exposure to low levels of air pollution is still insufficient. Early indicators, such as respiratory symptoms, need more attention. We made use of the fact that possible weak effects can be detected more easily when the relevant exposure and other determinants are well controlled. A postal questionnaire was sent to random samples of inhabitants registered as residing in the Vicinity of 55 centrally located air quality monitoring stations in Swedish towns. There were 6,109 questionnaires (76%) returned. Multivariate analyses with confounding control were used to examine the effects of different levels of criteria pollutants on the prevalence of symptoms. The ranges of the half year values were 9-32 and 2-16 mu g/m(3) for nitrogen dioxide and sulphur dioxide respectively. Logistic regression analyses showed higher risks for respiratory problems such as coughs, throat irritation and nose irritation among the persons most exposed, The associations were most obvious for nitrogen dioxide exposure among women. The suggested effects of air pollution exposure cannot be medically evaluated today but they are nevertheless interesting since they are found within common levels usually considered to be safe.