Developing benign syntheses using ion pairs via solvent-free mechanochemistry
Developing benign syntheses using ion pairs via solvent-free mechanochemistry
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DOI：
10.1039/d0gc01116a
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发表时间：
2020-06-07
期刊：
影响因子：
9.8
通讯作者：
Mack, James
中科院分区：
文献类型：
--
作者：
Ortiz-Trankina, Lianna N.;Crain, Jazmine;Mack, James
无溶剂的机械化学条件已被开发来研究离子配对的意义和使用弱碱来驱动亲核取代反应。这种方法利用缺乏溶剂壳的优势，结合更弱和更安全的碱，通过特定的离子配对途径驱动反应完成。最有效的反应包含更大和更极化的阳离子和阴离子对。
Solvent-free mechanochemical conditions have been developed to investigate the significance of ion pairing and the use of weak bases for driving forward nucleophilic substitution reactions. This approach takes advantage of the lack of solvent shells to incorporate weaker and safer bases to drive reactions to completion through specific ion pairing pathways. The most efficient reactions contained larger and more polarizable cation and anion pairs.