Quality Standards for Sample Processing, Transportation, and Storage in Hemostasis Testing
Quality Standards for Sample Processing, Transportation, and Storage in Hemostasis Testing
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DOI：
10.1055/s-0032-1319768
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发表时间：
2012-09-01
影响因子：
5.7
通讯作者：
Favaloro, Emmanuel J.
中科院分区：
文献类型：
--
作者：
Funk, Dorothy M. Adcock;Lippi, Giuseppe;Favaloro, Emmanuel J.
采集到枸橼酸钠抗凝剂中的止血试验样本易受与样本处理、运输和储存相关的分析前变量的影响。这些变量包括样品运输和储存的温度;样品处理后的稳定性;是否在室温、冷藏或冷冻条件下保存;离心方法;以及使用自动化生产线的潜在影响。确认这些变量，以及了解其对检测结果的潜在影响，对于报告高质量和准确的结果至关重要。本文讨论了与样品处理、运输和储存相关的分析前问题，并提出了样品处理的理想条件。
Samples for hemostasis testing drawn into sodium citrate anticoagulant are vulnerable to the effects of preanalytical variables associated with sample processing, transportation, and storage. These variables include the temperature at which samples are transported and stored; the stability of the samples once processed; whether maintained at room temperature, refrigerated, or frozen; methods of centrifugation; as well as the potential impact of using an automated line. Acknowledgment of these variables, as well as understanding their potential impact on assay results, is imperative to the reporting of high quality and accurate results. This article discusses the preanalytical issues associated with sample processing, transportation, and storage and also presents the ideal conditions for sample handling.