SCHISANDRA-CHINENSIS-DERIVED ANTIOXIDANT ACTIVITIES IN SHENG-MAI SAN A COMPOUND FORMULATION, IN-VIVO AND IN-VITRO
SCHISANDRA-CHINENSIS-DERIVED ANTIOXIDANT ACTIVITIES IN SHENG-MAI SAN A COMPOUND FORMULATION, IN-VIVO AND IN-VITRO
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DOI：
10.1002/ptr.2650090310
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发表时间：
1995-05-01
影响因子：
7.2
通讯作者：
KONG, YC
中科院分区：
文献类型：
--
作者：
KO, KM;YICK, PK;KONG, YC
生脉散是一种由人参、五味子和麦冬组成的中药复方制剂，用于治疗缺血性心脏病。在本研究中，我们已经证明了在体内和同上的抗氧化活性的SMS的存在下，其能力，以防止四氯化碳诱导的大鼠肝毒性和在体外系统中产生的超氧化物自由基的抑制。结果表明，五味子醇甲的抗氧化活性主要来源于五味子。
Sheng Mai San (SMS), a compound formulation in traditional Chinese medicine comprising Panar ginseng, Schisandra chinensis and Ophiopogon japonicus, is used for the treatment of ischaemic heart disease. In the present study, we have demonstrated the presence of both in vivo and in Ditto antioxidant activities in SMS, as indicated by its ability to protect against CCl4-induced hepatotoxicity in rats and to scavenge superoxide radicals generated in an in vitro system. Our results indicate that the antioxidant activity of SMS is derived mainly from Schisandra chinensis.