Columbia University microbeam: development of an experimental system for targeting cells individually with counted particles
Columbia University microbeam: development of an experimental system for targeting cells individually with counted particles
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哥伦比亚大学微束：开发一种用计数粒子单独靶向细胞的实验系统
DOI：
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
Wang Shaoh
中科院分区：
文献类型：
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作者：
Wu Liju;Wang Shaoh
哥伦比亚大学的微梁于1993年建造，1995年底完工。它已得到很好的建立，并常规用于用确定数量的α粒子照射高度局部化的空间区域中的细胞。通过使用这种探测器，有可能以传统宽场照射无法模拟的方式研究许多放射生物学问题。本报告介绍了哥伦比亚大学微束的发展和目前的能力，以及进行的初步研究。
Columbia University microbeam was constructed in 1993 and finished by the end of 1995. It is well established and used routinely to irradiate cells in a highly localized spatial region with a defined number of α-particles. By using this probe, it is possible to study a number of radiobiological questions in ways that cannot be simulated by using conventional broad-field exposures. This report describes the development and current capabilities of the Columbia University microbeam, as well as the preliminary researches undertaken.