Inhibitory potencies of fish oil hydroxy fatty acids on cellular lipoxygenases and platelet aggregation.
Inhibitory potencies of fish oil hydroxy fatty acids on cellular lipoxygenases and platelet aggregation.
复制标题
鱼油羟基脂肪酸对细胞脂氧合酶和血小板聚集的抑制作用。
DOI：
10.1016/0006-2952(91)90062-a
复制
发表时间：
1991
影响因子：
5.8
通讯作者：
Pham,PP
中科院分区：
文献类型：
--
作者：
Vanderhoek,JY;Schoene,NW;Pham,PP
在大鼠中，饮食中存在二十碳五烯酸和二十二碳六烯酸，由鲱鱼油补充剂提供，导致这些酸的羟基化代谢物的形成。这些代谢物被证明能够调节血小板和多形核白细胞的脂氧合酶活性，并抑制血小板聚集。
In rats, the presence of eicosapentaenoic and docosahexaenoic acids in the diet, provided by supplements of menhaden oil, led to the formation of hydroxylated metabolites of these acids. These metabolites were shown to be capable of regulating lipoxygenase activity of platelets and polymorphonuclear leukocytes and to inhibit platelet aggregation.