Molecularly imprinted sol-gel/Au@Ag core-shell nano-urchin localized surface plasmon resonance sensor designed in reflection mode for detection of organic acid vapors
Molecularly imprinted sol-gel/Au@Ag core-shell nano-urchin localized surface plasmon resonance sensor designed in reflection mode for detection of organic acid vapors
复制标题
反射模式设计的分子印迹溶胶-凝胶/Au@Ag核壳纳米海胆定域表面等离子体共振传感器用于检测有机酸蒸气
DOI：
10.1016/j.bios.2020.112639
复制
发表时间：
2020-12-01
影响因子：
12.6
通讯作者：
Hayashi, Kenshi
中科院分区：
文献类型：
--
作者：
Chen, Bin;Guo, Hao;Hayashi, Kenshi
提出了一种基于光纤反射模式的分子印迹溶胶-凝胶（MISG）/Au@Ag核壳结构NU传感器。该系统在反射模型中的紧凑结构设计有望作为便携式快速响应度传感探头用于实际应用。挥发性有机酸（OAs）是与特定人类疾病相关的生物挥发性有机蒸气的类似物。在这里，Au@Ag核-壳nanourchins表现出分支尖端的合成和沉积在氧化铟锡（ITO）玻璃上的小二聚体和微调集群，以产生增强的电场。然后将MISG溶液旋涂在基底上以制备MISG-LSPR传感器，并开发了三种类型的MISG用于检测己酸，庚酸和辛酸。归一化的光谱响应表明MISG-LSPR传感器对相应模板OA的选择性。与原生贝叶斯和线性判别分析的传感器响应，后者被检测到的建议的系统，单一和混合的OA蒸汽可以被分为单独的集群。这意味着所提出的MISG-LSPR传感器可以应用于单一蒸气或多种蒸气混合物的模式识别。
A molecularly imprinted sol-gel (MISG)/Au@Ag core-shell NU sensor is proposed for organic vapor detection in an optical fiber-based reflection mode. The compact structure design of the system in the reflection model is promising for practical use as a portable and rapid responsivity sensing probe. Volatile organic acids (OAs) are analogs to biogenetic volatile organic vapors related to specific human diseases. Here, Au@Ag core-shell nanourchins exhibiting branched tips were synthesized and deposited on indium tin oxide (ITO) glass in small dimer and trimmer clusters to generate an enhanced electric field. A MISG solution was then spin-coated on the substrate to fabricate MISG-LSPR sensors, and three types of MISGs were developed for the detection of hexanoic acid, heptanoic acid and octanoic acid. The normalized spectral response indicated selectivity of the MISG-LSPR sensors for the corresponding template OAs. With Native Bayes and linear discriminant analysis of the sensor responses, where the latter were detected by the proposed system, single- and mixed-OA vapors could be classified into separate clusters. This signified that the proposed MISG-LSPR sensor can be applied toward pattern recognition of single vapors or multiple vapor mixtures.