One-year prevalence of subthreshold and threshold DSM-IV generalized anxiety disorder in a nationally representative sample

One-year prevalence of subthreshold and threshold DSM-IV generalized anxiety disorder in a nationally representative sample
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DOI:
10.1002/da.1020
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发表时间:
2001-01-01
影响因子:
7.4
通讯作者:
Kessler, RC
Kessler, RC
中科院分区:
医学1区
文献类型:
--
作者:
Carter, RM;Wittchen, HU;Kessler, RC

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一些代表性人群的研究报告了DSM-III和DSM-III- r广泛性焦虑症(GAD)的患病率;然而,没有社区研究检验更严格的DSM-IV标准对患病率估计和合并症模式的影响。此外,过去基于“终生”症状评估的研究可能导致1年和点患病率估计的上限。数据来自德国一项具有全国代表性的样本研究,4181名18-65岁的成年人接受了为期12个月的慕尼黑复合国际诊断访谈(Munich-Composite International Diagnostic Interview)。严格定义的12个月阈值DSM-IV广泛性焦虑症患病率估计为1.5%;然而,3.6%的应答者在过去12个月中至少表现出广泛性焦虑症阈下综合征。女性(担忧10%,广泛性焦虑症2.7%)和老年受访者(担忧9.3%,广泛性焦虑症2.2%)的担忧和广泛性焦虑症比例更高。考虑到比以前的研究更广泛的诊断范围,GAD病例的高度共病被证实:所有12个月GAD病例中有59.1%符合重度抑郁症的标准,55.9%符合任何其他焦虑症的标准。总之,DSM-IV版广泛性焦虑症的患病率和合并率与DSM-III-R版广泛性焦虑症的患病率并无本质差异。与以前的报告相比,我们的研究结果的微小差异更可能归因于研究方法的差异,而不是DSM-IV诊断标准的变化。(C) 2001 Wiley-Liss, Inc。
Several studies of representative populations have reported prevalence rates of DSM-III and DSM-III-R generalized anxiety disorder (GAD); however, no community study has examined the effect of the stricter DSM-IV criteria on prevalence estimates and patterns of comorbidity. Furthermore, past studies based on "lifetime" symptom assessments might have led to upper-bound 1-year and point prevalence estimates. Data is presented from a national representative sample study of 4,181 adults in Germany, 18-65 years old, who were interviewed for DSM-IV disorders with the 12-month version of the Munich-Composite International Diagnostic Interview. The prevalence rate of strictly defined, 12-month threshold DSM-IV GAD was estimated to be 1.5%; however, 3.6% of respondents presented with at least subthreshold syndromes of GAD during the past 12 months. Higher rates of worrying and GAD were found in women (worrying 10%, GAD 2.7%) and in older respondents (worrying 9.3%, TAD 2.2%). Taking into account a wider scope of diagnoses than previous studies, a high degree of comorbidity in GAD cases was confirmed: 59.1% of all 12-month GAD cases fulfilled criteria for major depression, and 55.9% fulfilled criteria for any other anxiety disorder. In conclusion, prevalence and comorbidity rates found for DSM-IV GAD are not substantially different from rates reported for DSM-III-R GAD. The minor differences in our findings compared to previous reports are more likely attributable to differences in study methodology rather than changes in diagnostic criteria for DSM-IV. (C) 2001 Wiley-Liss, Inc.