Brain activation patterns during measurement of sub- and supra-second intervals
Brain activation patterns during measurement of sub- and supra-second intervals
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DOI：
10.1016/s0028-3932(03)00118-0
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发表时间：
2003-01-01
期刊：
影响因子：
2.6
通讯作者：
Miall, RC
中科院分区：
文献类型：
--
作者：
Lewis, PA;Miall, RC
不同的神经系统用于测量亚秒和几秒范围的时间持续时间的可能性已经得到了药理学操作，心理物理学和神经网络建模的支持。在这里，我们添加到这个文献中，使用功能磁共振成像隔离的大脑网络之间的差异，测量0.6和3秒的时间歧视任务与视觉歧视的控制。我们观察到活动在双侧颞叶和背外侧前额叶皮层，并在右半球前辅助运动区，额极，和下顶叶皮层在测量的两个时间间隔，这表明这些地区构成了一个系统，用于在这两个范围内的时间歧视。额盖，左小脑半球和中，上级颞回，都表现出显着更大的活动，在较短的时间间隔的测量过程中，支持的假设，运动系统是优先参与测量的亚秒间隔，并优先使用的听觉意象在测量过程中相同的。只有少数体素，落在左后扣带回和下顶叶，是更活跃的3s条件。总的来说，这项研究表明，虽然许多大脑区域被用于测量亚秒和超秒的时间持续时间，激活模式也有差异，这表明不同的组件被用于两个持续时间。(C)2003爱思唯尔科技有限公司版权所有。
The possibility that different neural systems are used to measure temporal durations at the sub-second and several second ranges has been supported by pharmacological manipulation, psychophysics, and neural network modelling. Here, we add to this literature by using fMRI to isolate differences between the brain networks which measure 0.6 and 3 s in a temporal discrimination task with visual discrimination for control. We observe activity in bilateral insula and dorsolateral prefrontal cortex, and in right hemispheric pre-supplementary motor area, frontal pole, and inferior parietal cortex during measurement of both intervals, suggesting that these regions constitute a system used in temporal discrimination at both ranges. The frontal operculum, left cerebellar hemisphere and middle and superior temporal gyri, all show significantly greater activity during measurement of the shorter interval, supporting the hypotheses that the motor system is preferentially involved in the measurement of sub-second intervals, and that auditory imagery is preferentially used during measurement of the same. Only a few voxels, falling in the left posterior cingulate and inferior parietal lobe, are more active in the 3 s condition. Overall, this study shows that although many brain regions are used for the measurement of both sub- and supra-second temporal durations, there are also differences in activation patterns, suggesting that distinct components are used for the two durations. (C) 2003 Elsevier Science Ltd. All rights reserved.