The expanding Asgard archaea invoke novel insights into Tree of Life and eukaryogenesis
The expanding Asgard archaea invoke novel insights into Tree of Life and eukaryogenesis
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DOI：
10.1002/mlf2.12048
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发表时间：
2022-12
期刊：
影响因子：
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通讯作者：
Zhichao Zhou;Yang Liu;Karthik Anantharaman;Meng Li
中科院分区：
文献类型：
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作者：
Zhichao Zhou;Yang Liu;Karthik Anantharaman;Meng Li
摘要将生命树上的生物划分为三个域(3D)树还是两个域(2D)树，长期以来一直存在争议。自1977年Carl Woese使用16S核糖体RNA序列作为进化标记发现古生物以来，我们对古生物多样性的认识以及不同生物谱系之间的进化关系都有了很大的进步。在这里，我们提出这一观点，以总结古生物多样性的进展和生命树概念的变化。同时，我们提供了基于基因组学/生理学的发现阿斯加德古菌谱系的最新进展，作为真核生物的最近亲缘关系。此外，我们还提出了未来研究的三个主要方向：探索“下一个”最接近的真核生物亲缘关系，从基因组和生理角度破译古代真核标志性蛋白和真核发生的功能，了解水平基因转移、病毒和可移动元件在真核发生中的作用。
Abstract The division of organisms on the Tree of Life into either a three‐domain (3D) tree or a two‐domain (2D) tree has been disputed for a long time. Ever since the discovery of Archaea by Carl Woese in 1977 using 16S ribosomal RNA sequence as the evolutionary marker, there has been a great advance in our knowledge of not only the growing diversity of Archaea but also the evolutionary relationships between different lineages of living organisms. Here, we present this perspective to summarize the progress of archaeal diversity and changing notion of the Tree of Life. Meanwhile, we provide the latest progress in genomics/physiology‐based discovery of Asgard archaeal lineages as the closest relative of Eukaryotes. Furthermore, we propose three major directions for future research on exploring the “next one” closest Eukaryote relative, deciphering the function of archaeal eukaryotic signature proteins and eukaryogenesis from both genomic and physiological aspects, and understanding the roles of horizontal gene transfer, viruses, and mobile elements in eukaryogenesis.