Evidence for transplacental and contact transmission of bluetongue virus in cattle
Evidence for transplacental and contact transmission of bluetongue virus in cattle
复制标题
DOI：
10.1136/vr.163.7.203
复制
发表时间：
2008-08-16
影响因子：
2.2
通讯作者：
Oura, C. A. L.
中科院分区：
文献类型：
--
作者：
Menzies, F. D.;Mccullough, S. J.;Oura, C. A. L.
本文提出的证据表明，蓝舌病病毒血清型 8 (BTV-8) 的野外毒株可经胎盘传播，并且也可通过直接接触途径传播。在无蚊季节期间，二十头怀孕小母牛从荷兰进口到北爱尔兰。进口前后的检测显示，其中8只动物体内有蓝舌病病毒抗体，但逆转录聚合酶链反应（RT-PCR）均未检测到病毒RNA。其中两只血清呈阳性的小母牛产下三头小牛，这些小牛显示出蓝舌病毒感染的证据（RT-PCR 阳性），其中一头小牛患有病毒血症。另外两只病毒血症动物（一头刚产下的荷兰小母牛和一头来自苏格兰的奶牛）也被发现感染了 BTV-8，有证据表明这两只动物可能是通过直接接触而感染的，可能是通过摄入感染了 BTV-8 的胎盘而感染的。
This paper presents evidence that a field strain of bluetongue virus serotype 8 (BTV-8) was transmitted transplacentally and that it was also spread by a direct contact route. Twenty pregnant heifers were imported from the Netherlands into Northern Ireland during the midge-free season. Tests before and after the animals were imported showed that eight of them had antibodies to bluetongue virus, but no viral RNA was detected in any of them by reverse transcriptase-PCR (RT-PCR). Two of the seropositive heifers gave birth to three calves that showed evidence of bluetongue virus infection (RT-PCR-positive), and one of the calves was viraemic. Two further viraemic animals (one newly calved Dutch heifer, and one milking cow originally from Scotland) were also found to have been infected with BTV-8 and evidence is presented that these two animals may have been infected by direct contact, possibly through the ingestion of placentas infected with BTV-8.