3D Printing of Anisotropic Hydrogels with Bioinspired Motion
3D Printing of Anisotropic Hydrogels with Bioinspired Motion
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DOI：
10.1002/advs.201800703
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发表时间：
2019-01-23
期刊：
影响因子：
15.1
通讯作者：
Yum, Kyungsuk
中科院分区：
文献类型：
--
作者：
Arslan, Hakan;Nojoomi, Amirali;Yum, Kyungsuk
生物有机体中的运动通常依赖于各向异性组织的功能排列，这些组织响应外部信号而线性扩张和收缩。然而，将这种各向异性行为应用到合成软材料中从而产生在生物有机体中看到的复杂运动的一般方法仍然是一个挑战。在这里，提出了一种生物灵感的方法，它使用温度响应型线性水凝胶致动器，类似于生物线性收缩元件，作为构建块来创建具有编程运动的三维(3D)结构。这种方法依赖于一种通用的3D打印方法，用于使用具有剪切稀释性的逃逸载体来构建水凝胶的3D结构。这项研究表明，垂直生长的双层结构的度规不相容导致了马鞍状的形状变化，这可以被进一步利用来产生从弯曲到扭转的各种生物激励运动。正交生长的双层结构在其形状转变过程中经历了由拉伸为主的运动到弯曲为主的运动的转变。这种方法的模块化性质，加上附加制造的灵活性，使得能够通过组装多个功能组件来制造具有复杂运动的多模块3D结构，这些组件又由简单的线性收缩元件组成。
Motion in biological organisms often relies on the functional arrangement of anisotropic tissues that linearly expand and contract in response to external signals. However, a general approach that can implement such anisotropic behavior into synthetic soft materials and thereby produce complex motions seen in biological organisms remains a challenge. Here, a bioinspired approach is presented that uses temperature-responsive linear hydrogel actuators, analogous to biological linear contractile elements, as building blocks to create three-dimensional (3D) structures with programmed motions. This approach relies on a generalizable 3D printing method for building 3D structures of hydrogels using a fugitive carrier with shear-thinning properties. This study demonstrates that the metric incompatibility of an orthogonally growing bilayer structure induces a saddle-like shape change, which can be further exploited to produce various bioinspired motions from bending to twisting. The orthogonally growing bilayer structure undergoes a transition from a stretching-dominated motion to a bending-dominated motion during its shape transformation. The modular nature of this approach, together with the flexibility of additive manufacturing, enables the fabrication of multimodular 3D structures with complex motions through the assembly of multiple functional components, which in turn consist of simple linear contractile elements.