Recent microfluidic devices for studying gamete and embryo biomechanics.
Recent microfluidic devices for studying gamete and embryo biomechanics.
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DOI:
10.1016/j.jbiomech.2015.02.039
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发表时间:
2015-06
影响因子:
2.4
通讯作者:
D. Lai;S. Takayama;Gary D. Smith
中科院分区:
文献类型:
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作者:
D. Lai;S. Takayama;Gary D. Smith
The technical challenges of biomechanic research such as single cell analysis at a high monetary cost, labor, and time for just a small number of measurements is a good match to the strengths of microfluidic devices. New scientific discoveries in the fertilization and embryo development process, of which biomechanics is a major subset of interest, is crucial to fuel the continual improvement of clinical practice in assisted reproduction. The following review will highlight some recent microfluidic devices tailored for gamete and embryo biomechanics where biomimicry arises as a major theme of microfluidic device design and function, and the application of fundamental biomechanic principles are used to improve outcomes of cryopreservation.