Binaural interaction in low-frequency neurons in inferior colliculus of the cat. I. Effects of long interaural delays, intensity, and repetition rate on interaural delay function.
Binaural interaction in low-frequency neurons in inferior colliculus of the cat. I. Effects of long interaural delays, intensity, and repetition rate on interaural delay function.
复制标题
猫下丘低频神经元的双耳相互作用。
DOI：
10.1152/jn.1983.50.4.981
复制
发表时间：
1983
影响因子：
2.5
通讯作者：
Yin,TC
中科院分区：
文献类型：
--
作者：
Kuwada,S;Yin,TC
对巴比妥麻醉猫的下丘 (IC) 中最佳频率较低的 197 个神经元的耳间相位敏感性进行了详细的定量研究。我们分析了单细胞对耳间延迟的反应，其中突发音调通过密封耳机传递到两只耳朵，并且一只耳朵的音调开始相对于另一只耳朵是不同的。对于大多数（80%）细胞来说，放电速率是耳间延迟的循环函数，其周期对应于刺激频率的周期。耳间延迟曲线的循环性质表明这些细胞对耳间相位差敏感。这些细胞分布在 IC 的整个低频区，但在内侧和尾部区域数量较少。具有多种反应模式的细胞将在高达 3,100 Hz 的刺激频率下表现出耳间相位敏感性，尽管在 2,500 Hz 以上此类细胞的数量显着减少。使用二分刺激，我们可以独立研究细胞对起始延迟和耳间期的敏感性。绝大多数 IC 细胞仅对耳间相位的变化做出反应，对起始延迟不敏感。然而，少数（7%）细胞表现出对起始延迟以及耳间相位差的敏感性，并且大多数这些细胞表现出起始反应。研究了改变双耳刺激强度相等或改变耳间强度差对平均耳间相位的影响。虽然一些神经元不受电平变化的影响，但其他神经元在平均和耳间强度变化方面表现出系统相移，并且在这些极端之间存在连续的敏感性分布。一些细胞还显示出耳间延迟曲线形状作为耳间强度差的函数的系统变化，特别是在很长的延迟时。这些转变可以解释为时间强度交易的一种形式。随着刺激重复率的变化，一些细胞表现出耳间延迟曲线的有序变化。其中一些变化与刺激抵消时发生的抑制作用一致。神经元的反应显示出对源自对侧声场的刺激的强烈偏差； 77% 的回答显示平均耳间相位角小于一个周期的 0.5，这是同侧音调的延迟。（摘要截断为 400 字）
Detailed, quantitative studies were made of the interaural phase sensitivity of 197 neurons with low best frequency in the inferior colliculus (IC) of the barbiturate-anesthetized cat. We analyzed the responses of single cells to interaural delays in which tone bursts were delivered to the two ears via sealed earphones and the onset of the tone to one ear with respect to the other was varied. For most (80%) cells the discharge rate is a cyclic function of interaural delay at a period corresponding to that of the stimulating frequency. The cyclic nature of the interaural delay curve indicates that these cells are sensitive to the interaural phase difference. These cells are distributed throughout the low-frequency zone of the IC, but they are less numerous in the medial and caudal zones. Cells with a wide variety of response patterns will exhibit interaural phase sensitivities at stimulating frequencies up to 3,100 Hz, although above 2,500 Hz the number of such cells decrease markedly. Using dichotic stimuli we could study the cell's sensitivity to the onset delay and interaural phase independently. The large majority of IC cells respond only to changes in interaural phase, with no sensitivity to the onset delay. However, a small number (7%) of cells exhibit a sensitivity to the onset delay as well as to the interaural phase disparity, and most of these cells show an onset response. The effects of changing the stimulus intensity equally to both ears or of changing the interaural intensity difference on the mean interaural phase were studied. While some neurons are not affected by level changes, others exhibit systematic phase shifts for both average and interaural intensity variations, and there is a continuous distribution of sensitivities between these extremes. A few cells also showed systematic changes in the shape of the interaural delay curves as a function of interaural intensity difference, especially at very long delays. These shifts can be interpreted as a form of time-intensity trading. A few cells demonstrated orderly changes in the interaural delay curve as the repetition rate of the stimulus was varied. Some of these changes are consonant with an inhibitory effect that occurs at stimulus offset. The responses of the neurons show a strong bias for stimuli that would originate from he contralateral sound field; 77% of the responses display mean interaural phase angles that are less than 0.5 of a cycle, which are delays to the ipsilateral tone.(ABSTRACT TRUNCATED AT 400 WORDS)