Plaque Distribution of Stenotic Middle Cerebral Artery and Its Clinical Relevance
Plaque Distribution of Stenotic Middle Cerebral Artery and Its Clinical Relevance
复制标题
DOI：
10.1161/strokeaha.111.618132
复制
发表时间：
2011-10-01
期刊：
影响因子：
8.3
通讯作者：
Cui, Li-Ying
中科院分区：
文献类型：
--
作者：
Xu, Wei-Hai;Li, Ming-Li;Cui, Li-Ying
背景与目的：显微解剖学研究表明，大脑中动脉（MCA）的大部分穿透性分支起源于干背上表面。使用高分辨率MRI，我们试图探索MCA动脉粥样硬化斑块分布及其与穿通动脉孔的临床相关性。方法回顾性分析86例动脉粥样硬化性MCA狭窄患者的影像学和临床资料。在高分辨率MRI上，斑块根据累及上、下、腹侧或背侧的MCA壁进行分类。分析斑块分布与临床表现的关系。结果：共对828张图像切片92例狭窄性mca进行了研究，其中有症状的40例，无症状的52例。总的来说，在251个已确定斑块的切片中，斑块位于腹侧（44.8%）和下壁（31.7%）的频率高于上壁（14.3%）和背壁（9.0%）
Background and Purpose-Microanatomy studies reveal that most penetrating branches of middle cerebral artery (MCA) arise from the dorsal-superior surface of the trunk. Using high-resolution MRI, we sought to explore the plaque distribution of MCA atherosclerosis and its clinical relevance in relation to the orifices of penetrating arteries.Methods-We retrospectively analyzed the imaging and clinical data of 86 patients with atherosclerotic MCA stenosis. On high-resolution MRI, plaques were categorized based on the involvement of the superior, inferior, ventral, or dorsal MCA wall. The relationship of plaque distribution and clinical presentation was analyzed.Results-A total of 92 stenotic MCAs (40 symptomatic and 52 asymptomatic) on 828 image slices were studied. Overall, of the 251 slices with identified plaques, plaques were more frequently located at the ventral (44.8%) and inferior (31.7%) wall as compared with the superior (14.3%) and dorsal wall (9.0%; P