A selective and sensitive off–on probe for palladium and its application for living cell imaging
A selective and sensitive off–on probe for palladium and its application for living cell imaging
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DOI：
10.1016/j.cclet.2015.09.003
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发表时间：
2016-02
影响因子：
9.1
通讯作者：
Ying Long;Jia Zhou;Meipan Yang;Bingqin Yang
中科院分区：
文献类型：
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作者：
Ying Long;Jia Zhou;Meipan Yang;Bingqin Yang
合理合成了一种新的罗丹明 B 衍生物 T1，并在甲醇-水中表现出选择性 Pd(II) 放大吸光度和 540 nm 以上的荧光发射。添加Pd(II)后，螺内酰胺环展开并形成1:1的金属配体络合物，可用于“肉眼”检测。此外，Pd2+在HepG2活细胞中的荧光成像实验显示了其在生物系统中的有价值的应用。
A new rhodamine B derivativeT1has been rationally synthesized and displayed selective Pd(II)-amplified absorbance and fluorescence emission above 540 nm in methanol–water. Upon the addition of Pd(II), the spirolactam ring was unfolded and a 1:1 metal-ligand complex formed, which can be used for “naked-eyes” detection. In addition, fluorescence imaging experiments of Pd2+in HepG2 living cells showed its valuable application in biological systems.