Accommodation — The Role of Natural Antibody and Complement in Discordant Xenograft Rejection

Accommodation — The Role of Natural Antibody and Complement in Discordant Xenograft Rejection
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调节——天然抗体和补体在不一致的异种移植排斥中的作用

DOI:
10.1007/978-3-642-97323-9_6
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发表时间:
1991
期刊:
影响因子:
--
通讯作者:
D. Cooper
D. Cooper
中科院分区:
--
文献类型:
--
作者:
F. Bach;J. Platt;D. Cooper

文献摘要

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随着供体器官短缺问题的日益严重,实现成功的不协调异种移植的潜在价值变得特别重要。在不协调异种移植成为临床现实之前,必须解决一些棘手的问题。然而,新的代理商,可以很好地改善某些不良的过程中涉及的异种移植排斥和分子生物学的力量,这可能会允许“设计”的免疫相容的器官,鼓励在这方面的努力。
With the increasing problem of donor organ shortages, the potential value of achieving successful discordant xenografting takes on special importance. Formidable problems must be solved before discordant xenografting can become a clinical reality. Nevertheless, the availability of new agents that may well ameliorate certain of the undesirable processes involved in the rejection of xenografts and the power of molecular biology, which may allow the “design” of immunologically compatible organs, encourage an effort in this regard.