Can Vascularity at Power Doppler US Help Predict Thyroid Malignancy?
Can Vascularity at Power Doppler US Help Predict Thyroid Malignancy?
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DOI：
10.1148/radiol.09091284
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发表时间：
2010-04-01
期刊：
影响因子：
19.7
通讯作者：
Kim, Eun-Kyung
中科院分区：
文献类型：
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作者：
Moon, Hee Jung;Kwak, Jin Young;Kim, Eun-Kyung
目的：回顾性评价能量多普勒超声（US）在描述血管和确定是否相结合的血管和可疑的灰度US功能是更有用的预测甲状腺恶性肿瘤的诊断性能比单独的灰度features.Materials and Methods：这是一个机构审查委员会批准的回顾性研究，与知情同意书的豁免。共纳入1024例患者（中位年龄51岁;范围16-83岁）的1083个甲状腺结节，包括886例女性（中位年龄50岁;范围16-83岁）和138例男性（中位年龄53岁;范围19-74岁）。根据灰阶超声标准，结节具有明显的低回声、边界不清、微钙化和高过宽的形状被归类为可疑结节。血管分布分为无、外周和结节内。比较了灰阶超声和能量多普勒超声特征的诊断性能，并按以下方式进行分类：标准1，任何单一的可疑灰阶超声特征;标准2，将任何血管作为可疑特征之一添加到标准1;标准3，将外周血管添加到标准1;标准4，将结节内血管添加到标准1;标准5，在标准1的基础上增加无血管分布;标准6，美国临床内分泌医师协会和医学内分泌学协会指南-所有低回声结节至少具有以下超声特征之一：边缘不规则，结节内血管斑点，高过宽的形状，或微钙化。良性结节多见结节内血管，恶性结节多无血管（P
Purpose:To retrospectively evaluate the diagnostic performance of power Doppler ultrasonography (US) in depicting vascularity and to determine whether the combination of vascularity and suspicious gray-scale US features is more useful in predicting thyroid malignancy than are gray-scale features alone.Materials and Methods:This was an institutional review board-approved retrospective study, with waiver of informed consent. A total of 1 083 thyroid nodules in 1024 patients (median age, 51 years; range, 16-83 years), consisting of 886 women (median age, 50 years; range, 16-83 years) and 138 men (median age, 53 years; range, 19-74 years), were included. Nodules with marked hypoechogenicity, noncircumscribed margins, microcalcifications, and taller-than-wide shape were classified as suspicious according to gray-scale US criteria. Vascularity was classified as none, peripheral, and intranodular. The diagnostic performance of gray-scale and power Doppler US features was compared and classified as follows: criterion 1, any single suspicious gray-scale US feature; criterion 2, addition of any vascularity as one of the suspicious features to criterion 1; criterion 3, addition of peripheral vascularity to criterion 1; criterion 4, addition of intranodular vascularity to criterion 1; criterion 5, addition of no vascularity to criterion 1; criterion 6, American Association of Clinical Endocrinologists and Associazione Medici Endocrinology guidelines-all hypoechoic nodules with at least one of the following US features: irregular margins, intranodular vascular spots, taller-than-wide shape, or microcalcifications.Results:Of 1083 nodules, 814 were benign and 269 were malignant. Intranodular vascularity was frequently seen in benign nodules and no vascularity was more frequent in malignant nodules (P