Restless legs syndrome prevalence and impact - REST general population study
Restless legs syndrome prevalence and impact - REST general population study
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DOI：
10.1001/archinte.165.11.1286
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发表时间：
2005-06-13
影响因子：
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通讯作者：
Ferini-Strambi, L
中科院分区：
文献类型：
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作者：
Allen, RP;Walters, AS;Ferini-Strambi, L
背景资料：不宁腿综合征（RLS）是一种常见的感觉运动障碍，其严重程度从仅仅令人烦恼到严重影响睡眠和生活质量，足以保证药物治疗。然而，以前的流行病学研究，未能确定那些有临床意义的RLS症状的患病率，并检查这组的生活影响和医疗经验。18岁）进行了采访，使用有效的诊断问题，以确定RLS症状的存在，频率和严重程度;报告RLS症状的受访者被问及医疗诊断和疾病的影响，并完成了简明健康调查表-36（SF-36）。标准确定的RLS专家为医学上显着的RLS（频率至少每周两次，痛苦至少中度）定义为“RLS患者”作为一组最有可能值得medical treatment.Results：在所有，15 391完全完成的问卷调查，获得在过去的一年中，RLS症状的任何频率报告的1114（7.2%）。773名受访者（5.0%）每周至少出现一次症状; 416名受访者（2.7%）每周至少出现2次症状，并报告为中度或重度痛苦。在这4.16例患者中，337例（81.0%）报告与初级保健医生讨论了他们的症状，只有21例（6.2%）被诊断为RLS。RLS患者的SF-36评分显着低于人口规范，匹配的患者与其他慢性医疗conditions.Conclusion：临床显着的RLS是常见的（患病率，2.7%），是诊断不足，并显着影响睡眠和生活质量。
Background: Restless legs syndrome (RLS), a common sensorimotor disorder, has a wide range of severity from merely annoying to affecting sleep and quality of life severely enough to warrant medical treatment. Previous epidemiological studies, however, have failed to determine the prevalence of those with clinically significant RLS symptoms and to examine the life effects and medical experiences of this group.Methods: A total of 16 202 adults (aged ! 18 years) were interviewed using validated diagnostic questions to determine the presence, frequency, and severity of RLS symptoms;, respondents reporting RLS symptoms were asked about medical diagnoses and the impact of the disorder and completed the Short Form-36 Health Survey (SF-36). Criteria determined by RLS experts for medically significant RLS (frequency at least twice a week, distress at least moderate) defined "RLS sufferers" as a group most likely to warrant medical treatment.Results: In all, 15 391 fully completed questionnaires were obtained; in the past year, RLS symptoms of any frequency were reported by 1114 (7.2%). Symptoms occurred at least weekly for 773 respondents (5.0%);, they occurred at least 2 times per week and were reported as moderately or severely distressing by 416 (2.7%). Of those 4.16 (termed RLS sufferers), 337 (81.0%) reported discussing their symptoms with a primary care physician, and only 21 (6.2%) were given a diagnosis of RLS. The SF-36 scores for RLS sufferers were significantly below population norms, matching those of patients with other chronic medical conditions.Conclusion: Clinically significant RLS is common (prevalence, 2.7%), is underdiagnosed, and significantly affects sleep and quality of life.