Alkali metal salts-assisted coupling reaction between fluorinated benzyl electrophiles and alkenylboronic acids
Alkali metal salts-assisted coupling reaction between fluorinated benzyl electrophiles and alkenylboronic acids
复制标题
DOI：
10.1039/d2nj04156a
复制
发表时间：
2022-09-29
影响因子：
3.3
通讯作者：
Xu，Bo
中科院分区：
文献类型：
--
作者：
Xie，Wenna;Liu，Shiwen;Xu，Bo
我们已经开发了一个通用的过渡金属自由的交叉偶联反应之间的氟化苄基亲电试剂和烯基硼酸的存在下，等量的碱金属盐，如K3PO4。这种不含过渡金属的方案对于广泛的底物提供了良好的化学产率，并表现出良好的官能团耐受性。
We have developed a versatile transition metal-free cross-coupling reaction between fluorinated benzyl electrophiles and alkenylboronic acids in the presence of the equivalent amount of alkali metal salts such as K3PO4. This transition metal-free protocol gives good chemical yields for a wide range of substrates and demonstrates good functional group tolerance.