Chronic stress burden, discrimination, and subclinical carotid artery disease in African American and Caucasian women
Chronic stress burden, discrimination, and subclinical carotid artery disease in African American and Caucasian women
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DOI：
10.1037/0278-6133.22.3.300
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发表时间：
2003-05-01
影响因子：
4.2
通讯作者：
Sutton-Tyrrell, K
中科院分区：
文献类型：
--
作者：
Troxel, WM;Matthews, KA;Sutton-Tyrrell, K
这项研究调查了 109 名非裔美国人和 225 名白人绝经前女性的压力综合指数（包括生活事件、持续压力、歧视和经济困难的衡量标准）与亚临床颈动脉疾病之间的关联。与白种人相比，非裔美国人的慢性压力更大，颈动脉内膜中层厚度 (IMT) 更高。仅在非裔美国人中，综合压力指数和不公平待遇与较高的 IMT 相关。这些影响部分是由生物危险因素介导的。报告遭受种族歧视的非裔美国人的颈动脉斑块比那些未报告遭受种族歧视的非裔美国人略多。结果表明，非裔美国人可能特别容易承受长期压力的负担。
This study examined the association between a composite index of stress that included measures of life events, ongoing stress, discrimination, and economic hardship and subclinical carotid disease among 109 African American and 225 Caucasian premenopausal women. African Americans reported more chronic stress and had higher carotid intima-media thickness (IMT) as compared with Caucasians. Among African Americans only, the composite stress index and unfair treatment were associated with higher IMT. These effects were partially mediated by biological risk factors. African Americans who reported experiencing racial discrimination had marginally more carotid plaque than did those who did not report experiencing racial discrimination. The results suggest that African Americans may be particularly vulnerable to the burden of chronic stress.